CROI 2016 Program at a Glance

Program and Agenda

Session P-C5 Poster Abstracts

Hall A/B

267 Tryptophan Metabolites Are Associated to Gut Microbiota in HIV-1 Infected Patients

2:45 PM-4:00 PM HIV and Microbiomes 260 Distinct Gut Microbiota Composition in Gay Men Muntsa Rocafort 1 ; Marc Noguera-Julian 1 ;Yolanda Guillen 2 ; Mariona Parera 1 ; Piotr Nowak 3 ; Falk Hildebrand 4 ; Georg Zeller 4 ; Anders Sönnerborg 3 ; Peer Bork 4 ; Roger Paredes 1 1 IrsiCaixa Inst forAIDSRsr,Badalona,Spain; 2 IrsiCaixa Inst forAIDSRsr, Barcelona,Spain; 3 Karolinska Inst,Stockholm,Sweden; 4 Structuraland ComputationalBiology,EuropeanMolecularBiologyLab,Heidelberg, Germany Jesús Luévano ; David B. Gootenberg; Jeffrey M. Paer; Bruce D.Walker; Douglas S. Kwon Ragon InstofMGH,MIT,andHarvard,Cambridge,MA,USA 262 Altered Gut Microbes Enhance Mucosal CD4 T Cell Infection and Depletion Ex Vivo Stephanie M. Dillon 1 ; Eric L. Lee 1 ; Andrew M. Donovan 1 ; Kejun Guo 1 ; Michael S. Harper 1 ; Daniel N. Frank 1 ; Martin D. McCarter 1 ; Mario L. Santiago 1 ; CaraWilson 2 1 UnivofColoradoAnschutzMedCampus,Aurora,CO,USA; 2 Univof ColoradoHosp,Aurora,CO,USA 263 Enhancement of Microbiota in Macaques Leads to Beneficial Immune Function Modulation Jennifer A. Manuzak 1 ;Tiffany Hensley-McBain 1 ; Charlene Miller 1 ; Alexander Zevin 1 ; Jason M. Brenchley 2 ; Jacob D. Estes 3 ; Stanley Langevin 1 ; R. Keith Reeves 4 ; Elias Haddad 5 ; Nichole Klatt 1 1 UnivofWashington,Seattle,WA,USA; 2 FrederickNatlLab forCancerRsr, Frederick,MD,USA; 3 FrederickNatlLab,LeidosBiomedRsr,Frederick,MD, USA; 4 HarvardUniv,Boston,MA,USA; 5 DrexelUniv,Philadelphia,PA,USA Ma Somsouk 1 ; IvanVujkovic-Cvijin 2 ; Montha Pao 1 ; PeterW. Hunt 1 ; SusanV. Lynch 1 ; Joseph M. McCune 1 1 UnivofCaliforniaSanFrancisco,SanFrancisco,CA,USA; 2 NIH,Bethesda, MD,USA 265 Effects of HAART Treatment on the Microbiome of HIV+ Patients Joshua Shorenstein 1 ; Netanya S. Utay 2 ; Basil Siewe 3 ; David Asmuth 4 ; Rob Knight 1 1 UnivofCaliforniaSanDiego,SanDiego,CA,USA; 2 UnivofTexasMed BranchatGalveston,Galveston,TX,USA; 3 RushUniv,Chicago, IL,USA; 4 UnivofCaliforniaDavisMedCntr,Sacramento,CA,USA 266 Diet Effects on the Gut Microbiome of People Living With HIV-1 Javier Rivera Pinto 1 ; Marc Noguera-Julian 1 ; Carla Estany 2 ; Muntsa Rocafort 1 ;Yolanda Guillen 3 ; Mariona Parera 1 ; Pep Coll 1 ; Bonaventura Clotet 2 ; Roger Paredes 1 ; M. Luz Calle 4 1 IrsiCaixa Inst forAIDSRsr,Badalona,Spain; 2 LluitaContra laSIDAFndn, GermansTrias iPujolUnivHosp,Barcelona,Spain; 3 IrsiCaixa Inst forAIDS Rsr,Barcelona,Spain; 4 UnivdeVic,Barcelona,Spain 264 Fecal Microbial Transplantation: Safety and Engraftment During Treated HIV Infection 261 Impact of HIV-Associated Changes in the Gut Microbiome on Disease Progression

Babilonia Barqasho 1 ; Ujjwal Neogi 1 ; Lilly Schwieler 1 ; Göran Engberg 1 ; MariusTroseid 2 ; Anders Sönnerborg 1 ; Piotr Nowak 1 1 Karolinska Inst,Stockholm,Sweden; 2 OsloUnivHosp,UllevålHosp, Oslo,Norway

Session P-C6 Poster Abstracts

Hall A/B

2:45 PM-4:00 PM SIV Models of Pathogenesis 268 Chronic Semen Exposure Reduces SIVmac251 Vaginal Infection in Rhesus Macaques Shaheed A. Abdulhaqq 1 ; Melween I. Martinez 2 ; Guobin Kang 3 ; David Beaumont 4 ; Jan Münch 5 ; GeorgiaTomaras 4 ; Preston A. Marx 6 ; Qingsheng Li 7 ; Edmundo N. Kraiselburd 8 ; Luis J. Montaner 9 1 OregonHlth&SciUniv,Beaverton,OR,USA; 2 CaribbeanPrimateRsr Cntr,San Juan,PR,USA; 3 UnivofNebraska,Lincoln,NE,USA; 4 DukeUniv, Durham,NC,USA; 5 UnivofUlm,Ulm,Germany; 6 TulaneUnivSchofPH andTropMed,NewOrleans,LA,USA; 7 SchofBiologicalScisandNebraska Cntr forVirology,UnivofNebraska,Lincoln,NE,USA; 8 SchofMed,Univof PuertoRico,San Juan,PR,USA; 9 TheWistar Inst,Philadelphia,PA,USA 269 Single-Cell Expression Profiling Reveals Immune Dysfunction in Acute SIV Infection Sama Adnan ; Premeela A. Rajakumar; James M. Billingsley; R. P. Johnson EmoryUniv,Atlanta,GA,USA 270 CD169 Is a Marker of Immune Activation in SIV Infection but Not Rectal Susceptibility Magnus Hallor 1 ; Meropi Aravantinou 2 ; Rachel Singer 2 ; Agegnehu Gettie 3 ; James Blanchard 4 ; Jeffrey Lifson 5 ; Michael Piatak 5 ; Andres Salazar 6 ; Melissa Robbiani 2 ; Nina Derby 2 1 LinkopingUniv,Linkoping,Sweden; 2 PopCouncil,NewYork,NY,USA; 3 AaronDiamondAIDSRsrCntr,NewYork,NY,USA; 4 TulaneNatlPrimate RsrCntr,Covington,LA,USA; 5 FrederickNatlLab,Frederick,MD,USA; 6 Oncovir, Inc,Washington,DC,USA Abderaouf Damouche 1 ;Thierry Lazure 2 ;Veronique Avettand- Fenoel 3 ; Nicolas Huot 4 ; Christine Rouzioux 5 ; Jacqueline Capeau 6 ; Michaela Müller-Trutwin 4 ; Nathalie Dereuddre-Bosquet 7 ; Roger Le Grand 7 ; Olivier Lambotte 8 ; Christine Bourgeois 7 1 UnivParisSud,UMR1184, Ivrysurseine,France; 2 HôpitauxdeParis, HôpitauxUniversitairesParis-Sud,LeKremlin-Bicêtre,France; 3 EA7327, UnivParisDescartes,Paris,France; 4 InstPasteur,Paris,France; 5 Necker Hosp,AP-HP,Paris,France; 6 INSERMUMR-S938,CDRSaint-Antoine, Paris,France; 7 UnivParisSud,UMR1184,LeKremlin-Bicêtre,Fontenay auxRoses,France; 8 UnivParisSud,UMR1184,LeKremlin-Bicêtre,France 272 a4-Integrin Antibody Blocks Monocyte Traffic and Decreases SIV Pathology in DRGs Jessica R. Lakritz 1 ; DerekThibault 1 ; Jake A. Robinson 1 ; Jennifer Campbell 1 ; Andrew D. Miller 2 ;Tricia H. Burdo 1 1 BostonColl,ChestnutHill,MA,USA; 2 CornellUniv, Ithaca,NY,USA 271 Adipose Tissue and HIV Infection

Poster Listings

80

CROI 2016