CROI 2016 Program at a Glance

Program and Agenda

314 Deleterious Effect of KIR-HLA-Associated Gag Sites on Clinical Outcome in CRF01_AE Masahiko Mori 1 ; NuanjunWichukchinda 2 ; Reiko Miyahara 3 ; Archawin Rojanawiwat 2 ; Panita Pathipvanich 4 ;Toshiyuki Miura 3 ; Michio Yasunami 3 ; Koya Ariyoshi 3 ; Pathom Sawanpanyalert 2 1 UnivofOxford,Oxford,UK; 2 MinistryofPH,Nonthaburi,Thailand; 3 Inst ofTropMed,NagasakiUniv,Nagasaki, Japan; 4 LampangHosp,Lampang, Thailand 315 Blockade of KIR2DL1/3 Significantly Improves the Anti-HIV-1 Activity of KIR+ NK Cells Christian Körner 1 ; Camille R. Simoneau 2 ; Mitchell E. Granoff 2 ; Björn Corleis 2 ; Eileen P. Scully 3 ; Douglas S. Kwon 2 ; Stephanie Jost 2 ; Marcus Altfeld 1 1 HeinrichPette Inst,Hamburg,Germany; 2 Ragon InstofMGH,MITand Harvard,Cambridge,MA,USA; 3 MassachusettsGeneralHosp,Boston, MA,USA 316 IFN-a Augments NK-Mediated ADCC Lysis via VRC01 or HIV-1 Infected Subject Plasma 2:45 PM-4:00 PM Novel HIV Reservoirs 330 Persistence of HIV-Infected Alveolar Macrophages After Suppressive ART Feiyu Hong ; Heather M. Michael; Shulin M. Qin; Lawrence Kingsley; Deborah McMahon; Meghan E. Fitzpatrick; Alison Morris; JohnW. Mellors UnivofPittsburgh,Pittsburgh,PA,USA 331 Evidence of HIV Evolution in Lymphatic and Cancer Tissues in ART+ Patients Rebecca Rose 1 ; Susanna L. Lamers 1 ; David J. Nolan 2 ; Debra L. Garcia 3 ; Marco Salemi 2 ; Ekaterina Maidji 4 ; Cheryl Stoddart 4 ; Elyse Singer 5 ; Michael S. McGrath 4 1 Bioinfoexperts,LLC,Thibodaux,LA,USA; 2 EmergingPathogens Inst,Univ ofFlorida,Gainesville,FL,USA; 3 AIDSandCancerSpecimenResource,San Francisco,CA,USA; 4 UnivofCaliforniaSanFrancisco,SanFrancisco,CA, USA; 5 NatlNeurologicalAIDSBank,LosAngeles,CA,USA 332 Role of Transitional-Memory T Cells in Productive HIV Reservoir in ULTRASTOP Patients Chiraz Hamimi 1 ; Sidonie Lambert 2 ; Ruxandra Calin 3 ; Guislaine Carcelain 1 ;Yasmine Dudoit 3 ; Lambert Assoumou 2 ;Vincent Calvez 2 ; Dominique Costagliola 2 ; Christine Katlama 2 ; Brigitte Autran 1 1 INSERM,UMR-S1135,Paris,France; 2 SorbonneUnivs,Paris,France; 3 APHP,Pitié-SalpêtrièreUnivHosp,Paris,France 333 Drug Activity in PrEP Breakthroughs Has a Transient Effect on SHIV DNA Reservoirs Mian-er Cong; Chou-Pong Pau;Walid Heneine; Gerardo Garcia- Lerma CDC,Atlanta,GA,USA CostinTomescu 1 ; Brian Ross 1 ; PabloTebas 2 ; Luis J. Montaner 1 1 TheWistar Inst,Philadelphia,PA,USA; 2 UnivofPennsylvania, Philadelphia,PA,USA Session P-F1 Poster Abstracts Hall A/B

334 Germinal Centre T and B Cells in Lymph Node Fine- Needle Biopsies During HIV Infection John J. Zaunders 1 ;William Hey-Cunningham 2 ;Yin Xu 2 ; Chester Pearson 2 ; Michelle Bailey 2 ; Brad Milner 1 ; Andrew Field 1 ; David Cooper 3 ; Anthony Kelleher 2 ; Kersten K. Koelsch 4 1 StVincent’sHosp,Darlinghurst,Australia; 2 UnivofNewSouthWales, Sydney,Australia; 3 Kirby Inst,Sydney,Australia; 4 Kirby Inst,UnivofNew SouthWales,Sydney,Australia 335 Tcm CD4 T-Cell Infection Associates With Immune Failure and HIV Persistence on ART Vincent C. Marconi 1 ; Emily Ryan 2 ; Luca Micci 3 ; Amelie Pagliuzza 4 ; Sol Aldrete 1 ; Keith Delman 1 ; Jacob D. Estes 5 ; Nicolas Chomont 6 ; Rafick Sekaly 7 ; Mirko Paiardini 2 1 EmoryUnivSchofMed,Atlanta,GA,USA; 2 YerkesNatlPrimateRsrCntr, EmoryUniv,Atlanta,GA,USA; 3 EmoryUniv,Atlanta,GA,USA; 4 CRCHUM, Montreal,QC,Canada; 5 FrederickNatlLab,LeidosBiomedRsr,Frederick, MD,USA; 6 UnivdeMontréal,Montreal,QC,Canada; 7 CaseWestern ReserveUniv,Cleveland,OH,USA 2:45 PM-4:00 PM HIV Reservoir: Measurement and Mechanisms of Persistence 336 Sustained HIV Release by Single Persisting CD4+ T Cells During Latency Disruption Jason M. Hataye 1 ; Joseph P. Casazza 2 ; David Ambrozak 1 ; Eli Boritz 2 ; TakuyaYamamoto 3 ; Daniel C. Douek 2 ; Alan S. Perelson 4 ; Richard A. Koup 2 1 NIH,Bethesda,MD,USA; 2 VRC,NIAID,NIH,Bethesda,MD,USA; 3 Osaka Univ,Osaka, Japan; 4 LosAlamosNatlLab,LosAlamos,NM,USA 337 Analysis of HIV Proviruses in Clonally Expanded Cells In Vivo Francesco R. Simonetti 1 ; Jonathan Spindler 2 ; XiaolinWu 3 ; Shawn Hill 2 ;Wei Shao 4 ; JohnW. Mellors 5 ; Stephen H. Hughes 6 ; Mary F. Kearney 6 ; Frank Maldarelli 6 ; John M. Coffin 7 1 UnivofMilan,Milan, Italy; 2 HIVDynamicsandReplicationProg,NCI, Frederick,MD,USA; 3 FrederickNatlLab,Frederick,MD,USA; 4 Leidos BiomedRsr, Inc,Frederick,MD,USA; 5 UnivofPittsburgh,Pittsburgh,PA, USA; 6 NCI,Frederick,MD,USA; 7 TuftsUniv,Boston,MA,USA 338 Viral Evolution Analysis for the Distinction of True HIV-1 Elite-Controller Patients Maria Pernas ; Concepcción Casado; Isabel Olivares; Cecilio López- Galindez; for theThe HIV Controllers Consortium of the AIDS Spanish Network. InstdeSaludCarlos III,Madrid,Spain 339 Optimization of PCR Amplicons to Predict Clonality of Full-Length HIV-1 Sequences Sarah B. Laskey 1 ; Katherine M. Bruner 2 ; Robert Siliciano 3 1 JohnsHopkinsUniv,Baltimore,MD,USA; 2 JohnsHopkinsUnivSchof Med,Baltimore,MD,USA; 3 HowardHughesMed Inst,Baltimore,MD,USA Session P-F2 Poster Abstracts Hall A/B

Poster Listings

57

CROI 2016