CROI 2016 Program at a Glance

Program and Agenda

Session P-C3 Poster Abstracts

Hall A/B

253 Does Reduced HLA-I Downregulation by HIV-2 Nef Contribute to Functional Cure? Sophie M. Andrews 1 ; ChisatoYamada 2 ; Simon Brackenridge 1 ; Thushan de Silva 3 ;Tao Dong 1 ; Sarah L. Rowland-Jones 1 1 UnivofOxford,Oxford,UK; 2 HokkaidoUniv,Sapporo, Japan; 3 Univof Sheffield,Sheffield,UK 254 Selective Loss of T-bet and Eomes in HIV-Specific CD4+ T Cells During HIV Infection Marcus Buggert 1 ; Marianne Jansson 2 ; Korey Demers 1 ; Johanna Tauriainen 3 ; Anders Sönnerborg 3 ; Michael A. Eller 4 ; Merlin L. Robb 4 ; Steven G. Deeks 5 ; Annika Karlsson 3 ; Michael R. Betts 1 1 UnivofPennsylvania,Philadelphia,PA,USA; 2 LundUniv,Lund,Sweden; 3 Karolinska Inst,Stockholm,Sweden; 4 USMilitaryHIVRsrProg,Walter ReedArmy InstofRsr,SilverSpring,MD,USA; 5 SanFranciscoGeneral Hosp,SanFrancisco,CA,USA 255 Antioxidants Improve Lung Immunity and T-Cell Proliferation in Immune Non-Responders Sushma K. Cribbs 1 ; Lou Ann Brown 1 ; Mirko Paiardini 2 ; Colleen Kraft 1 ; David Rimland 1 ; Jeffrey L. Lennox 1 ;Vincent C. Marconi 1 ; David Guidot 1 1 EmoryUnivSchofMed,Atlanta,GA,USA; 2 YerkesNatlPrimateRsrCntr, EmoryUniv,Atlanta,GA,USA 256 The Effect of KIR-Mediated Immunity on HIV Clinical Outcome in South Africa Masahiko Mori 1 ; Ellen M. Leitman 1 ; Bruce D.Walker 2 ;Thumbi P. Ndungu 3 ; Philip Goulder 1 1 UnivofOxford,Oxford,UK; 2 Ragon InstofMGH,MIT,andHarvard, Cambridge,MA,USA; 3 UnivofKwaZulu-Natal,Durban,SouthAfrica 257 Immunomodulatory Effects of Recreational Marijuana Use in Youth LivingWith HIV-1 Ashok Dinasarapu 1 ; Carla Mavian 2 ; Alberto Riva 2 ; Sofia Appelberg 3 ; JulieWilliams 2 ; John Sleasman 4 ; Maureen Goodenow 2 1 EmoryUniv,Atlanta,GA,USA; 2 UnivofFlorida,Gainesville,FL,USA; 3 Karolinska Inst,Stockholm,Sweden; 4 DukeUnivSchofMed,Durham, NC,USA 258LB T Regulatory Cell Depletion in Controller Macaques Reactivates SIV and Boosts CTLs Cristian Apetrei ; Egidio Brocca-Cofano; Jennifer L. Stock; Benjamin B. Policicchio; HeTianyu; Kevin D. Raehtz; Cuiling Xu; Ivona Pandrea UnivofPittsburgh,Pittsburgh,PA,USA 259LB Increased Effector CD8 Lymphocyte Trafficking to Lymph Nodes Induced by hetIL-15 George N. Pavlakis 1 ; AntonioValentin 1 ; Cristina K. Bergamaschi 1 ; Dionysios K.Watson 1 ; Costantinos Petrovas 2 ; Xintao K. Hu 1 ; James I. Mullins 3 ; Barbara K. Felber 4 1 NCIatFrederick,Frederick,MD,USA; 2 NIH,Bethesda,MD,USA; 3 Univof Washington,Seattle,WA,USA; 4 NCI,Rockville,MD,USA

2:45 PM-4:00 PM Genetics and Cell Biology of HIV Infection 246 BST-2, TRIM22, and RAD51 in Host Susceptibility to HIV-1 Infection and Virus Control Ravesh Singh 1 ;Vivek Naranbhai 2 ; Lise Jamieson 2 ; Nigel Garrett 2 ; Salim A. Karim 2 ;Thumbi P. Ndungu 3 1 HIVPathogenesisProg,UnivofKwa-ZuluNatal,Durban,SouthAfrica; 2 CAPRISA,UnivofKwaZulu-Natal,Durban,SouthAfrica; 3 Univof KwaZulu-Natal,Durban,SouthAfrica 247 6-Amino-Acid Insertion/Deletion Polymorphism in TIM1 Confers Protections Against HIV1 1 UnivofMilan,Brescia, Italy; 2 UnivofMilan,Milan, Italy; 3 Scientific Inst forRecoveryandCareE.Medea,Milan, Italy; 4 IrsiCaixa Inst forAIDSRsr, Badalona,Spain; 5 S.MariaAnnunziataHosp,Florence, Italy; 6 Univof Antioquia,Medellin,Colombia 248 MicroRNA Profile in CD8 T Cells FromHIV-Infected Individuals and Disease Progression Montserrat Plana 1 ; Lander Egaña-Gorroño 1 ; Alberto C. Guardo 1 ; Manel Enric Bargalló 1 ; ElisendaVilaplana 2 ;Tuixent Escribà 3 ; Iñaki Perez 1 ; Josep María Gatell 4 ; Felipe García 4 ; Mireia Arnedo 1 ; for the HIV Controllers Consortium of the AIDS Spanish Network 1 IDIBAPS,Barcelona,Spain; 2 UnivdeVic,Barcelona,Spain; 3 Fundació Clínic,Barcelona,Spain; 4 HospClínicdeBarcelona,Barcelona,Spain 249 P2X7 Purinergic Receptors Are Required for HIV-1 Infection and Inflammation Talia Swartz ; Meagan K. O’Brien; Natasha D. Durham; Anthony M. Esposito; Nina Bhardwaj; Benjamin K. Chen IcahnSchofMedatMountSinai,NewYork,NY,USA 250 Characterization of Plasma Exosome Protein Cargo in HIV Patients on ART Sukrutha Chettimada ; Lorenz David;Vikas Misra; Dana Gabuzda Dana-FarberCancer Inst,Boston,MA,USA 251 A Model of CD4 TCM Cell Death in HIV Infection Based on a Gene Expression Signature Irma Saulle 1 ; Michela Masetti 2 ; Mara Biasin 2 ; DariaTrabattoni 2 ; Manuela Sironi 3 ; Christian Brander 4 ; FrancescaVichi 5 ; Sergio Lo Caputo 5 ; Mario Clerici 2 ;Wbeimar Aguilar-Jiménez 6 Gustavo Olvera-García 1 ;Tania Aguilar-García 1 ; Ivan Imaz- Rosshandler 2 ; Claudia Rangel-Escareño 2 ; Lorena Orozco 2 ; Irma Aguilar-Delfín 2 ; JoelVázquez-Pérez 1 ; Joaquín Zúñiga 1 ; Santiago Pérez-Patrigeon 3 ; Enrique Espinosa 1 1 Natl InstofRespiratoryDiseases,MexicoCity,Mexico; 2 Natl Instof GenomicMed,MexicoCity,Mexico; 3 Natl InstofNutrition,MexicoCity, Mexico 2:45 PM-4:00 PM Immunopathogenesis 252 IL-7 Responsiveness Is Impaired in CD4 T Cells FromHIV Immune Failure Patients Thao Nguyen ; Michael M. Lederman; Scott M. Sieg CaseWesternReserveUniv,Cleveland,OH,USA Session P-C4 Poster Abstracts Hall A/B

Poster Listings

55

CROI 2016