CROI 2016 Program at a Glance

Program and Agenda

209LB Kinesin-1 and Nup358 Cooperatively Mediate the Nuclear Import of HIV During Infection Edward Campbell ; Adarsh Dharan; SarahTalley LoyolaUnivChicago,Maywood, IL,USA

231 Mode of Sexual Transmission Can Exert an Impact on Shaping the HIV-1 Founder Virus Damien C.Tully 1 ; Colin B. Ogilvie 1 ; Rebecca E. Batorsky 1 ; Eric S. Rosenberg 2 ; Kenneth H. Mayer 3 ; Heiko Jessen 4 ; Sergei Kosakovsky

Pond 5 ; Marcus Altfeld 6 ; Jonathan Carlson 7 ;Todd M. Allen 1 1 Ragon InstofMGH,MITandHarvard,Cambridge,MA,USA; 2 MassachusettsGeneralHosp,Boston,MA,USA; 3 TheFenway Inst,

Session P-B3 Poster Abstracts

Hall A/B

2:45 PM-4:00 PM Viral Genetics: Effects on Transmission, Disease, and Reinfection 226 HIV-1 Subtypes: 5 LTR-Leader Sequence Variants and Late HIV Seroconversion Ma Luo 1 ; Raghavan Sampathkumar 2 ; Ian MacArthur 2 ; Joel Scott- Herridge 2 ; Paul Sandstrom 1 ; Joshua Kimani 3 ; Francis Plummer 1 1 NatlMicrobiologyLabofCanada,Winnipeg,MB,Canada; 2 Univof Manitoba,Winnipeg,MB,Canada; 3 UnivofNairobi,Nairobi,Kenya 227 HIV-1 Stop Codon Usage and Its Clinical Impacts in Rural Ugandan Patients 1 MassachusettsGeneralHosp,Boston,MA,USA; 2 BCCntr forExcellence inHIV/AIDS,Vancouver,BC,Canada; 3 MbararaUnivofSciandTech, Mbarara,Uganda; 4 UnivofCaliforniaSanFrancisco,SanFrancisco,CA, USA; 5 HarvardMedSch,Boston,MA,USA 228 Intrahost Viral Competition and Archiving Dynamics in HIV-1 Superinfection Antoine Chaillon; Davey M. Smith; Susan J. Little; Gemma Caballero; Douglas D. Richman; GabrielWagner UnivofCaliforniaSanDiego,SanDiego,CA,USA 229 Spatiotemporal Dynamics of Drug Resistance Evolution and Persistence of RT-SHIV Alison F. Feder 1 ; Christopher Kline 2 ; Shiu-Lok Hu 3 ; Brandon Keele 4 ; Dmitri A. Petrov 1 ; Pleuni S. Pennings 5 ; Zandrea Ambrose 2 1 StanfordUniv,Stanford,CA,USA; 2 UnivofPittsburgh,Pittsburgh, PA,USA; 3 UnivofWashington,Seattle,WA,USA; 4 FrederickNatlLab, Frederick,MD,USA; 5 SanFransiscoStateUniv,SanFrancisco,CA,USA 2:45 PM-4:00 PM Defining the Sequence Characteristics of Transmitted Viruses 230 Limited Evidence for a Bias Toward Consensus Residues Upon HIV-1 Transmission Morgane Rolland 1 ; Julie Ake 2 ; Merlin L. Robb 2 ; Nelson L. Michael 3 1 USMilitaryHIVRsrProg,SilverSpring,MD,USA; 2 USMilitaryHIVRsr Prog,WalterReedArmy InstofRsr,SilverSpring,MD,USA; 3 USMilitary HIVRsrProg,Bethesda,MD,USA Guinevere Q. Lee 1 ;Viviane D. Lima 2 ;Wendy Zhang 2 ;Yap Boum 3 ; Simone H. Kigozi 3 ; A. Rain Mocello 4 ; PeterW. Hunt 4 ; Jeffrey N. Martin 4 ; David R. Bangsberg 5 ; P. Richard Harrigan 2 Session P-B4 Poster Abstracts Hall A/B

FenwayHlth,Boston,MA,USA; 4 HIVClinicPraxis Jessen,Berlin,Germany; 5 UnivofCaliforniaSanDiego,SanDiego,CA,USA; 6 HeinrichPette Inst, Hamburg,Germany; 7 MicrosoftRsr,Redmond,WA,USA 232 Characterizing the Multiplicity of HIV Founder Variants During Sexual Transmission Antoine Chaillon 1 ; Sara Gianella 1 ; Susan J. Little 1 ; Christy Anderson 1 ; Gemma Caballero 1 ; Francis Barin 2 ; Sergei Kosakovsky Pond 1 ; Douglas D. Richman 1 ; Davey M. Smith 1 ; Sanjay R. Mehta 1 1 UnivofCaliforniaSanDiego,SanDiego,CA,USA; 2 François-Rabelais Univ,Tours,France 2:45 PM-4:00 PM Pathogenesis of Mucosal Transmission 284 Progesterone (P4) Indirectly Increases Susceptibility to HIVWithin Genital Mucosa Jason Neidleman 1 ; Joseph Chen 2 ; Nargis Kohgadai 2 ; Janis A. Müller 3 ; JeremyW. Martin 1 ; Jan Münch 3 ; Ruth M. Greenblatt 2 ; Linda Giudice 2 ; Warner C. Greene 1 ; Nadia R. Roan 2 1 Gladstone Insts,SanFrancisco,CA,USA; 2 UnivofCaliforniaSan Francisco,SanFrancisco,CA,USA; 3 UnivofUlm,Ulm,Germany 285 Seminal Plasma Induces Inflammation and Enhances HIV-1 Infection in Cervical Explants Andrea Introini 1 ; AnnelieTjernlund 1 ; Stéphanie Boström 1 ; Bo Hejdeman 2 ; Anna Gibbs 1 ; Frideborg Bradley 1 ; Kristina Broliden 3 1 Karolinska Inst,Stockholm,Sweden; 2 Södersjukhuset,Stockholm, Sweden; 3 KarolinskaUniv,Stockholm,Sweden 286 The Effect of Condomless Receptive Anal Intercourse on the Rectal Mucosa in MSM Colleen F. Kelley 1 ; JingYang 1 ; GregoryTharp 1 ; Kirk A. Easley 2 ; Mark Mulligan 1 ; Patrick Sullivan 1 ; Steven E. Bosinger 3 ; Rama Amara 3 ; for the Emory Center for AIDS Research 1 EmoryUniv,Atlanta,GA,USA; 2 EmoryUnivRollinsSchofPH,Atlanta, GA,USA; 3 YerkesNatlPrimateRsrCntr,EmoryUniv,Atlanta,GA,USA 287 Reduced Peripheral a4ß7+ CD4+ T Cells CorrelateWith Mucosal CD4+ T Cell Loss in AHI Alexandra Schuetz 1 ; Chayada Sajjaweerawan 1 ; Nittaya Phanuphak 2 ; Rungsun Rerknimitr 3 ; PonpenTantivayakul 2 ; Nitiya Chomchey 2 ; Merlin L. Robb 4 ; Robin Dewar 5 ; Mark de Souza 2 ; Jintanat Ananworanich 6 ; for the RV254/SEARCH 010 and RV304/SEARCH 013 Study Groups 1 USAFRIMS,Bangkok,Thailand; 2 SEARCH,Bangkok,Thailand; 3 ChulalongkornUniv,Bangkok,Thailand; 4 USMilitaryHIVRsrProg, WalterReedArmy InstofRsr,SilverSpring,MD,USA; 5 FrederickCancer RsrandDevelopCntr,Frederick,MD,USA; 6 MilitaryHIVRsrProg, Bethesda,MD,USA Session P-C8 Poster Abstracts Hall A/B

Poster Listings

CROI 2016 105

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