CROI 2016 Program at a Glance

Program and Agenda

1060 Global Variation in the Impact of Male Circumcision in Preventing HIV Among MSM Lilith K.Whittles 1 ; Kate M. Mitchell 1 ; Romain Silhol 1 ; DobromirT. Dimitrov 2 ; Marie-Claude Boily 1 1 ImperialCollLondon,London,UK; 2 FredHutchinsonCancerRsrCntr, Seattle,WA,USA 1061 What Does Community HIV Testing Really Cost in South Africa? Guillermo Martínez Pérez 1 ; Aline Aurore Niyibizi 2 ; Jessie Kurkunar 1 ; Amir Shroufi 3 ; Sarah Jane Steele 4 ; GillesVan Cutsem 3 1 MédecinsSansFrontières,SouthAfrica&Lesotho,Eshowe,SouthAfrica; 2 MédecinsSansFrontières,Roma,Lesotho; 3 MédecinsSansFrontières, CapeTown,SouthAfrica; 4 MédecinsSansFrontières,SouthAfrica& Lesotho,CapeTown,SouthAfrica 1062 Costs of Hybrid Mobile Multi-Disease TestingWith High HIV Test Coverage, East Africa Wei Chang 1 ; Gabriel Chamie 1 ; HarshaThirumurthy 2 ;Tamara Clark 1 ; Edwin Charlebois 1 ; Maya Petersen 3 ; Moses R. Kamya 4 ; DianeV. Havlir 1 ; James G. Kahn 1 ; for the Sustainable East Africa Research for Community Health (SEARCH) Collaboration 1 UnivofCaliforniaSanFrancisco,SanFrancisco,CA,USA; 2 UnivofNorth CarolinaatChapelHill,ChapelHill,NC,USA; 3 UnivofCaliforniaBerkeley, Berkeley,CA,USA; 4 MakerereUnivCollofHlthScis,Kampala,Uganda 1063 Targeting Serodiscordant Couples Within Home HIV Testing Campaigns: A Modeling Study SarahT. Roberts 1 ; Aditya S. Khanna 2 ; RuanneV. Barnabas 1 ; Steven M. Goodreau 1 ; Jared M. Baeten 1 ; Connie M. Celum 1 ; Susan L. Cassels 3 1 UnivofWashington,Seattle,WA,USA; 2 UnivofChicago,Chicago, IL, USA; 3 UnivofCaliforniaSantaBarbara,SantaBarbara,CA,USA 2:45 PM-4:00 PM Host Factors and Cell Response to Infection 199 Transcriptional Regulation of the APOBEC3 Repertoire Through the CBFß/RUNX Axis Brett D. Anderson 1 ; Reuben S. Harris 2 1 UnivofMinnesota,Minneapolis,MN,USA; 2 HowardHughesMed Inst, Minneapolis,MN,USA 200 Is Endogenous APOBEC3H an HIV-1 Transmission Barrier? 1 UnivofMinnesota,Minneapolis,MN,USA; 2 UnivofWashington,Seattle, WA,USA; 3 FredHutchinsonCancerRsrCntr,Seattle,WA,USA; 4 Howard HughesMed Inst,Minneapolis,MN,USA 201 Characterization of Novel Human APOBEC3A Variants Matthew Hernandez ; Lara Manganaro; Marcel Ooms; Lubbertus C. Mulder;Veronica Iannucci; Marsha Dillon-White; Sandra N.Terry; Ekta Sharma;Viviana A. Simon IcahnSchofMedatMountSinai,NewYork,NY,USA JiayiWang 1 ; Allison M. Land 1 ; Brian J. Hoium 1 ; EricW. Refsland 1 ; Elizabeth M. Luengas 1 ; Romel D. Mackelprang 2 ;William L. Brown 1 ; Michael Emerman 3 ; Jairam R. Lingappa 2 ; Reuben S. Harris 4 THURSDAY, FEBRUARY 25, 2016 Session P-A4 Poster Abstracts Hall A/B

202 CBFß Protects HIV-1 Vif FromMDM2-Mediated Degradation Yusuke Matsui ; Keisuke Shindo; Kayoko Nagata; NoriyoshiYoshinaga; Kotaro Shirakawa; Masayuki Kobayashi; AkifumiTakaori-Kondo KyotoUniv,Kyoto, Japan 203 MARCH8 Restricts HIV-1 Infection by Reducing Envelope Incorporation Into Virions KenzoTokunaga 1 ;TakuyaTada 1 ;Yanzhao Zhang 1 ;Takayoshi Koyama 1 ; MinoruTobiume 1 ;YasukoTsunetsugu-Yokota 1 ; ShojiYamaoka 2 ; Hideaki Fujita 3 1 Natl Instof InfectiousDiseases,Tokyo, Japan; 2 TokyoMedandDental Univ,Tokyo, Japan; 3 Nagasaki IntlUniv,Nagasaki, Japan 204 Sirtuins Modulate HIV Integration and Replication: New Cellular Anti-HIV Targets Michelino Di Rosa 1 ; Ilaria Gnemmi 2 ; Beatrice Riva 2 ; Ubaldina Galli 2 ; Armando Genazzani 2 ; Pier Luigi Canonico 2 ; Marilia R. Pinzone 1 ; Fabrizio Condorelli 2 ; Giuseppe Nunnari 1 1 UnivofCatania,Catania, Italy; 2 SchofPharm,UnivofPiemonte OrientaleA.Avogadro,Novara, Italy 205 SAMHD1 Phosphorylation Affects dNTPase Activity and HIV-1 Replication Capacity 1 IrsiCaixa Inst forAIDSRsr,Badalona,Spain; 2 Valld Hebron Instde Recerca,Barcelona,Spain; 3 LluitaContra laSIDAFndn,GermansTrias i PujolUnivHosp,Barcelona,Spain; 4 CentrodeBiologíaMolecularSevero Ochoa (ConsejoSuperiorde InvestigacionesCientíficasUAM),Madrid, Spain 206 Novel Mutant HIV-1 Strains With Greater Resistance to Cynomolgus Macaque TRIMCyp Tahmina Sultana 1 ; Emi E. Nakayama 1 ; Satoshi E.Tobita 2 ;Yohei Seki 3 ; Akatsuki Saito 4 ; Masako Nomaguchi 5 ; Akio Adachi 5 ; Hirofumi Akari 4 ; Tatsuo E. Shioda 1 1 Rsr Inst forMicrobialDiseases,OsakaUniv,Suita, Japan; 2 OsakaUniv, Suita, Japan; 3 KyotoUniv,Kyoto, Japan; 4 Inst forVirusRsr,KyotoUniv, Kyoto, Japan; 5 InstofHlthBioScis,TheUnivofTokushimaGradSch, Tokushima, Japan 207 The G1/S Specific Cyclin D2 Acts As a Viral Restriction Factor in Primary Macrophages Ester Ballana 1 ; Roger Badia 1 ; Maria Pujantell 1 ; Eva Riveira-Muñoz 1 ; José A. Esté 1 ; Bonaventura Clotet 2 1 IrsiCaixa Inst forAIDSRsr,Badalona,Spain; 2 LluitaContra laSIDAFndn, GermansTrias iPujolUnivHosp,Barcelona,Spain 208 Characterizing Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection Monica Golumbeanu 1 ; Pejman Mohammadi 2 ; Sébastien Desfarges 3 ; Céline Hernandez 4 ; Manfredo Quadroni 5 ; AmalioTelenti 6 ; Niko Beerenwinkel 1 ; Angela Ciuffi 3 1 ETHZürich,Basel,Switzerland; 2 NewYorkGenomeCntr,NewYork,NY, USA; 3 InstofMicrobiology,LausanneUnivHospandUnivofLausanne, Lausanne,Switzerland; 4 InstdeBiologiede l’ÉcoleNormaleSupérieure, Paris,France; 5 UnivofLausanne,Lausanne,Switzerland; 6 Univof CaliforniaSanDiego,SanDiego,CA,USA Roger Badia 1 ; Eva Riveira-Muñoz 1 ; Maria Pujantell 1 ; JavierTorres- Torronteras 2 ; Bonaventura Clotet 3 ; Luis Menéndez-Arias 4 ; Ramón Martí 2 ; Ester Ballana 1 ; José A. Esté 1

Poster Listings

CROI 2016 104