CROI 2017 Program and Information

Program and Agenda

256 P2X PURINERGIC RECEPTORS AS THERAPEUTIC TARGETS OF HIV-1 INFECTION AND INFLAMMATION Talia Swartz 1 , Natasha Durham 2 , Alexandra Soare 1 , Meagan O’Brien 1 , Nina Bhardwaj 1 , Benjamin K. Chen 1 1 Icahn Sch of Med at Mt Sinai, New York, NY, USA, 2 Tufts Univ, Boston, MA, USA 257 AGE AND HIV DO NOT SYNERGISTICALLY IMPACT T-CELL MATURATION OR ACTIVATION Shelli Farhadian 1 , Emilie Jalbert 2 , Yanhong Deng 3 , Matthew B. Goetz 4 , Lesley Park 5 , Amy Justice 3 , Robert Dubrow 3 , Brinda Emu 1 , for the VACS Project Team 1 Yale Univ, New Haven, CT, USA, 2 Univ of Colorado, Aurora, CO, USA, 3 VA Greater Los Angeles Hlth Care System, Los Angeles, CA, USA, 4 Stanford Med, Stanford, CA, USA, 5 VA Connecticut Hlthcare System, West Haven, CT, USA 258 CELLULAR IMMUNE ACTIVATION IN THE ERA OF CART AND AN AGING HIV+POPULATION Lesley R. de Armas , Suresh Pallikkuth, Rajendra Pahwa, Stefano Rinaldi, Varghese George, Li Pan, Allan Rodriguez, Margaret Fischl, Gordon Dickinson, Savita Pahwa Univ of Miami, Miami, FL, USA 259 ADAR1, A TARGET TO BOOST HIV-1 IMMUNE RESPONSE Maria Pujantell , Ester Ballana, Eva Riveira-Muñoz, Bonaventura Clotet, Jose A. Este IrsiCaixa Inst for AIDS Rsr, Badalona, Spain 260LB LIVER INFLAMMATION CORRELATESWITH SIV LEVELS AND IS ONLY PARTLY REVERSEDWITH CART Bridget Fisher 1 , Rachel Brown 1 , MatthewWood 1 , Richard Green 2 , Cole Fisher 1 , Michael Gale 2 , Guido Silvestri 3 , Ann Chahroudi 3 , Nichole Klatt 2 , Donald Sodora 1 1 Cntr for Infectious Disease Rsr, Seattle, WA, USA, 2 Univ of Washington, Seattle, WA, USA, 3 Emory Univ, Atlanta, GA, USA 261 CD57+CYTOTOXIC CD4+EFFECTOR T CELLS INCREASE IN CHRONIC HIV INFECTION Chansavath Phetsouphanh 1 , Jodi Meyerowitz 1 , Lyle Murray 1 , Dominique Goedhals 2 , Cloete Van Vuuren 2 , Sarah Fidler 3 , Paul Klenerman 1 , John Frater 1 1 Univ of Oxford, Oxford, UK, 2 Univ of Free State Med Sch, Bloemfontein, South Africa, 3 Imperial Coll London, London, UK 262 TARGETING LCWITH ANTI-LANGERINHIV FUSIONMONOCLONAL AB PROMOTES TFH DIFFERENTIATION Jérôme Kervevan 1 , Aurélie Chaigneau 1 , Sandy Zurawski 2 , Marion Bonnet 3 , Romain Marlin 4 , Marie-Thérèse Nugeyre 4 , Elisabeth Menu 4 , Gerard Zurawski 2 , Yves Levy 1 , Sylvain Cardinaud 1 1 INSERM, Créteil, France, 2 Baylor Inst for Immunol Rsr, Dallas, TX, USA, 3 Univ of Cardiff, Cardiff, UK, 4 Inst Pasteur, Paris, France 263 HIV-1-INFECTION–ASSOCIATED CHANGES IN THE HUMAN CD4+ T-CELL PROTEOME Johannes Nemeth 1 , Valentina Vongrad 2 , Karin Metzner 2 , Victoria P. Strouvelle 2 , Rainer Weber 2 , Patrick Pedrioli 3 , Ruedi Aebersold 3 , Huldrych F. Günthard 2 , Ben Collins 3 1 Cntr for Infectious Disease Rsr, Seattle, WA, USA, 2 Univ of Zürich, Zürich, Switzerland, 3 ETH Zürich, Zürich, Switzerland Poster P-D3 CD4 T CELLS: MORE THAN JUST HELP Poster Hall - 4 EF 2:30 PM - 4:00 PM

Poster Sessions • Thursday

CROI 2017 171