CROI 2017 Program and Information

Program and Agenda

240 IMPACT OFMUCOSAL CMV AND EBV REPLICATION ON ENTERIC MICROBIOME DURING HIV INFECTION Antoine Chaillon 1 , Sara Gianella 2 , Ece A. Mutlu 3 , Phillip A. Engen 3 , Robin M. Voigt 3 , Ali Keshavarzian 3 , John Losurdo 3 , Steven Lada 2 , Masato Nakazawa 2 , Alan Landay 3 1 Univ of California San Diego, San Diego, CA, USA, 2 Univ of California San Diego, La Jolla, CA, 3 Rush Univ Med Cntr, Chicago, IL, USA 241 EFFECT OF HIV STATUS, CMV, AND EBV REPLICATION ON MUCOSAL GENE EXPRESSION IN THE GUT Sara Gianella 1 , Antoine Chaillon 2 , Ece A. Mutlu 3 , Phillip A. Engen 3 , Robin M. Voigt 3 , Ali Keshavarzian 3 , John Losurdo 3 , Steven Lada 1 , Masato Nakazawa 1 , Alan Landay 3 1 Univ of California San Diego, La Jolla, CA, USA, 2 Univ of California San Diego, San Diego, CA, USA, 3 Rush Univ, Chicago, IL, USA 251 TELMISARTAN DOES NOT IMPROVE LYMPHNODE OR FAT FIBROSIS IN TREATED HIV INFECTION Netanya S. Utay 1 , Douglas Kitch 2 , Carl Fichtenbaum 3 , Michael M. Lederman 4 , Jacob D. Estes 5 , Clara Magyar 6 , Karin Klingman 7 , Judith S. Currier 6 , Jordan E. Lake 1 , for the A5317 Team 1 Univ of Texas, Galveston, TX, USA, 2 Harvard Univ, Boston, MA, USA, 3 Univ of Cincinnati, Cincinnati, OH, USA, 4 Case Western Reserve Univ, Cleveland, OH, USA, 5 Frederick Natl Lab for Cancer Rsr, Frederick, MD, USA, 6 Univ of California Los Angeles, Los Angeles, CA, USA, 7 DAIDS, NIAID, Bethesda, MD, USA 252 PHARMACOLOGIC INHIBITION OF IDO BLUNTS FEATURES OF SIV-RELATED CHRONIC INFLAMMATION Richard M. Dunham 1 , Kevin W. Brown 1 , James M. Billingsley 2 , Zhong-Min Ma 3 , Gregory K. Tharp 2 , Christopher J. Miller 3 , Steven E. Bosinger 2 , Brian A. Johns 1 , David Favre 1 1 GlaxoSmithKline, Durham, NC, USA, 2 Yerkes Natl Primate Rsr Cntr, Atlanta, GA, USA, 3 Univ of California Davis, Davis, CA, USA 253 HIV-SPECIFIC ANTIBODIES ENHANCE TYPE I INTERFERON PRODUCTION FROMPLASMACYTOID DCS Rebecca Veenhuis 1 , Zachary Freeman 1 , Jack Korleski 1 , Alessandra Tomasi 1 , Austin Boesch 2 , Margaret Ackerman 2 , Joseph B. Margolick 1 , Joel Blankson 1 , Michael Chattergoon 1 , Andrea Cox 1 1 The Johns Hopkins Univ, Baltimore, MD, USA, 2 Dartmouth Coll, Hanover, NH, USA 254 TARGETING TYPE I INTERFERON-MEDIATED IMMUNE ACTIVATION TO CONTROL HIV INFECTION Anjie Zhen 1 , Mayra A. Carrillo 1 , Valerie Rezek 1 , David Brooks 2 , Scott G. Kitchen 1 1 Univ of California Los Angeles, Los Angeles, CA, USA, 2 Princess Margaret Cancer Cntr, Toronto, Ontario, Canada 255 METFORMIN REDUCES T-CELL EXHAUSTION IN A CLINICAL TRIAL OF HIV-INFECTED ADULTS ON ART Glen Chew 1 , Dominic Chow 1 , Scott A. Souza 1 , Lindsay Kohorn 1 , Richard M. Watanabe 2 , Ivo Sah Bandar 1 , Eun-Young Park 1 , Mary Margaret Byron 1 , Lishomwa C. Ndhlovu 1 , Cecilia Shikuma 1 1 Univ of Hawaii, Honolulu, HI, USA, 2 Univ of Southern California, Los Angeles, CA, USA Poster P-D2 INFLAMMATION AND IMMUNITY Poster Hall - 4 EF 2:30 PM - 4:00 PM

Poster Sessions • Thursday

CROI 2017 170