CROI 2016 Program at a Glance

Program and Agenda

Session P-G2 Poster Abstracts

Hall A/B

Session P-G3 Poster Abstracts

Hall A/B

2:45 PM-4:00 PM Virology and Basic Neuroscience 393 Productive Infection of HIV in Astrocytes via a CD4- Independent, CXCR4-Dependent Mech Guanhan Li 1 ; Caroline Anderson 1 ; Eugene O. Major 1 ; Avindra Nath 2 1 NINDS,NIH,Bethesda,MD,USA; 2 NIH,Bethesda,MD,USA 394 A Unique In Vitro Neuropathic Phenotype of Clade D Transmitted/Founder Viruses Analise Gruenewald 1 ; Alexander J. Gill 1 ; George M. Shaw 2 ; Dennis L. Kolson 2 1 UnivofPennsylvania,Philadelphia,PA,USA; 2 PerelmanSchofMed,Univ ofPennsylvania,Philadelphia,PA,USA 395 Neurotoxicity Screening of Antiretroviral Drugs With Human iPSC-Derived Neurons 1 SanfordBurnhamPrebysMedDiscovery Inst,La Jolla,CA,USA; 2 Univof CaliforniaSanDiego,SanDiego,CA,USA; 3 UnivatBuffalo,StateUnivof NewYork,Buffalo,NY,USA 396 Chronic Low-Level HIV-1 Tat Expression Promotes a Neurodegenerative Phenotype Alfred Chin ; Alex M. Dickens; Amanda L.Trout; Jackie Lovett; Joelle Dorskind; Norman Haughey JohnsHopkinsUnivSchofMed,Baltimore,MD,USA 397 Glutaminase Regulates Extracellular Vesicles Release in HIV-1 Infected Macrophages BeiqingWu ;Yunlong Huang; Runze Zhao;Yuju Li; Jialin C. Zheng UnivofNebraskaMedCntr,Omaha,NE,USA 398 HIV-1 Replication Dynamics in the CNS of TB- Coinfected Individuals Ikanyeng D. Seipone 1 ;Thumbi P. Ndungu 2 ; Ravesh Singh 1 ;Vinod Patel 3 1 HIVPathogenesisProg,UnivofKwa-ZuluNatal,Durban,SouthAfrica; 2 UnivofKwaZulu-Natal,Durban,SouthAfrica; 3 InkosiAlbertLuthuliHosp and theNelsonRMandelaSchofMed,UnivofKwaZulu-Natal,Durban, SouthAfrica 399 Glial Transcriptional Responses Follow HIV-1 Infection in a Humanized Mouse Brain Weizhe Li ; Li E.Wu; Jaclyn Knibbe-Hollinger; Santhi Gorantla; Howard E. Gendelman; LarisaY. Poluektova UnivofNebraskaMedCntr,Omaha,NE,USA Sandy Hinckley 1 ; Sean Sherman 1 ; Brookie M. Best 2 ; Jeremiah Momper 2 ; Qing Ma 3 ; Scott R. Letendre 2 ; Ron Ellis 2 ; Anne Bang 1

2:45 PM-4:00 PM Central Nervous System: HIV Entry, Reservoirs, and Compartmentalization 400 CNS Compartmentalization of HIV-1 and Sensitivity to Neutralizing Antibodies Karl Stefic 1 ; Antoine Chaillon 2 ; Mélanie Bouvin-Pley 3 ; Alain Moreau 3 ; Martine Braibant 3 ; Guillaume Gras 4 ; Frederic Bastides 4 ; Louis Bernard 4 ; Francis Barin 3 1 CHUdeTours,Tours,France; 2 UnivofCaliforniaSanDiego,SanDiego, CA,USA; 3 François-RabelaisUniv,Tours,France,Tours,France; 4 CHUde Tours,Tours,France 401 HIV Compartmentalization in the CNS Is Associated With Neurocognitive Impairment Natalie M. Bowman 1 ; Sarah B. Joseph 1 ; Laura P. Kincer 1 ; Sarah Yosief 1 ; Serena S. Spudich 2 ; Joseph J. Eron 1 ; RichardW. Price 3 ; Ronald I. Swanstrom 1 ; Kevin R. Robertson 1 ; for theTHINC Group 1 UnivofNorthCarolinaatChapelHill,ChapelHill,NC,USA; 2 YaleUniv SchofMed,NewHaven,CT,USA; 3 UnivofCaliforniaSanFrancisco,San Francisco,CA,USA 402 Persistent HIV-1 in the CNS During Therapy: Evidence of a Viral Reservoir in the CNS 1 UnivofNorthCarolinaatChapelHill,ChapelHill,NC,USA; 2 YaleUniv SchofMed,NewHaven,CT,USA; 3 UnivofCaliforniaSanFrancisco,San Francisco,CA,USA 403 Bone MarrowMacrophages Are a Potential Source of CNS Virus With SIV-Encephalitis Jaclyn C. Mallard 1 ; Brittany Rife 2 ; David J. Nolan 2 ; Graham Beck 1 ; Emily Papazian 1 ; Russell Simons 1 ;Tricia H. Burdo 1 ; Marco Salemi 2 ; Kenneth C.Williams 1 1 BostonColl,ChestnutHill,MA,USA; 2 EmergingPathogens Inst,Univof Florida,Gainesville,FL,USA 404 Peripheral Immune Activation Modulates HIV RNA Entry to CSF in Early Acute Infection Alexandra Schuetz 1 ; Suteeraporn Pinyakorn 2 ; Leah Le 3 ;Yuwadee Phuang-Ngern 1 ; Eugène Kroon 4 ; Linda Jagodzinski 5 ;Thep Chalermchai 4 ;VictorValcour 6 ; Jintanat Ananworanich 5 ; Serena S. Spudich 3 ; for the RV254/SEARCH 010 Study Group 1 USAFRIMS,Bangkok,Thailand; 2 USMilitaryHIVRsrProg,WalterReed Army InstofRsr,SilverSpring,MD,USA; 3 YaleUnivSchofMed,New Haven,CT,USA; 4 SEARCH,Bangkok,Thailand; 5 MilitaryHIVRsrProg, Bethesda,MD,USA; 6 UnivofCaliforniaSanFrancisco,SanFrancisco, CA,USA 405 Early CSF Viremia and CNS T-Cell Infiltrate in a Nonaccelerated SHIV Infection Model SandhyaVasan 1 ; Piyanate Sunyakumthorn 2 ; Matthew D.Wegner 2 ; Eric Lombardini 2 ; Joanna M. Hellmuth 3 ; Jintanat Ananworanich 4 ;Victor Valcour 3 ; Robert O’Connell 2 ; Serena S. Spudich 5 ; Nelson L. Michael 6 1 USMilitaryHIVRsrProg,APO,AP,USA; 2 ArmedForcesRsr InstofMed Scis,Bangkok,Thailand; 3 UnivofCaliforniaSanFrancisco,SanFrancisco, CA,USA; 4 MilitaryHIVRsrProg,Bethesda,MD,USA; 5 YaleUnivSchof Med,NewHaven,CT,USA; 6 USMilitaryHIVRsrProg,Bethesda,MD,USA Sarah B. Joseph 1 ; Laura P. Kincer 1 ; Natalie M. Bowman 1 ; SarahYosief 1 ; Angela Kashuba 1 ; Kevin R. Robertson 1 ; Serena S. Spudich 2 ; Joseph J. Eron 1 ; RichardW. Price 3 ; Ronald I. Swanstrom 1

Poster Listings

84

CROI 2016