CROI 2016 Program at a Glance

Program and Agenda

Session S-6 Symposium

Ballroom B/C

Session S-7 Symposium

Room 304/306

CME

CME

4:00 PM-6:00 PM Pathogenesis and Consequences of Metabolic Complications Target audience: This session is directed to clinicians and scientists who are interested in understanding the pathogenesis and consequences of metabolic complications in patients with HIV infection. Level of knowledge: It is assumed that participants are familiar with the basic concept that HIV may cause immune activation and that HIV may increase the risk of metabolic complications. Objectives: At the completion of the session, participants will be able to: • Describe immunologic mechanisms thought to drive metabolic complications in HIV infected adults and children • Describe the current understanding of the pathogenesis and clinical consequences of visceral adiposity, NASH/NAFLD, and bone disease in HIV infected adults and children Conveners Todd T. Brown ,The JohnsHopkins University,Baltimore,MD,USA Allison R. Eckard ,MedicalUniversityof SouthCarolina,Charleston,SC,USA 4:00 123 Visceral Adiposity in the Modern HIV Treatment Era Grace A. McComsey ,CaseWesternReserve Univ,Cleveland,OH,USA

4:00 PM-6:00 PM Location, Location, Location: The Lymph Node

Target audience: This session is directed to clinicians and scientists who are interested in understanding HIV/SIV immunology, virology, and pathogenesis. Level of knowledge: It is assumed that participants are familiar with basic concepts of how immune responses are generated to infections or vaccines, and how HIV/SIV replicates. Objectives: At the completion of the session, participants will be able to: • Describe the architecture of the lymph node, and where immune responses are generated • Describe how antigen presenting cells within lymph nodes are involved in orchestrating immune responses • Describe where HIV/SIV replicates in lymph nodes • Describe why antiviral CD8 T cells have difficulty suppressing HIV/SIV replication in lymph nodes Symposium Conveners

Wednesday, February 24, 2016 • Oral Sessions

Susan Moir ,National InstitutesofHealth, National InstituteofAllergyand Infectious Diseases,Bethesda,MD,USA Ashley T. Hasse ,UniversityofMinnesota, Minneapolis,MN,USA 4:00 127 Visualizing the Early Events of

Antigen Recognition by B Cells Facundo Batista ,FrancisCrick Inst, London,UK

4:30 124 NAFLD and NASH in HIV Infection Elizabeth C.Verna ,ColumbiaUniv,New York,NY,USA

4:30 128 Are Follicular Dendritic Cells a Reservoir for HIV? Michael C. Carroll ,HarvardUniv,Boston, MA,USA 5:00 129 Imaging Lymphoid Tissues to Understand Viral Persistence and Impaired Function Jacob D. Estes ,FrederickNatlLab,Leidos BiomedRsr,Frederick,MD,USA 5:30 130 The Lymph Node, Cytotoxic T cell, and HIV/SIV Infections Elizabeth Connick ,UnivofColorado, Denver,CO,USA

5:00 125 Immunopathogenesis of Metabolic Complications in Treated HIV Infection Suzanne M. Crowe ,Burnet Inst,Melbourne, Australia 5:30 126 What Exactly Does Antiretroviral Therapy Do to Bone?

Patrick Mallon ; for theUCDHIVMolecular ResearchGroup,UnivCollDublin,Dublin, Ireland

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CROI 2016

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