CROI 2015 Program and Abstracts

Poster Listings

Session P-Q7 Poster Session

Poster Hall

779 Body Composition Outcomes at 96Weeks in the SECOND-LINE RCT DXA Substudy Mark A. Boyd 1 ; Janaki Amin 1 ; PatrickW. Mallon 2 ; Jennifer F. Hoy 3 ; Samuel Ferret 4 ;Waldo Belloso 5 ; Praphan Phanuphak 6 ; Sean Emery 1 ; David A. Cooper 1 SECOND-LINE study group 1 University of New South Wales Australia, Sydney, Australia; 2 University College Dublin, Dublin, Ireland; 3 Monash University/Alfred Hospital, Melbourne, Australia; 4 Hopital Saint Louis, Paris, France; 5 Hospital Italiano, Buenos Aires, Argentina; 6 Thai Red Cross AIDS Research Centre, Bangkok, Thailand 780 Bone Quality by Quantitative Ultrasound at the Radius Does Not Differ in ART-Naïve HIV+ and HIV- RwandanWomen Eugene Mutimura 1 ; Qiuhu Shi 2 ; Donald R. Hoover 3 ; Kathryn Anastos 4 ; Emmanuel Rudakemwa 5 ; Jean Claude Dusingize 1 ; Jean D’Amour Sinayobye 1 ; MichaelTYin 6 1 Regional Alliance for Sustainable Development, Kigali, Rwanda; 2 School of Health Sciences and Practice, New York Medical College, New York, NY, US; 3 State University of New Jersey, New Brunswick, NJ, US; 4 Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, US; 5 King Faisal Hospital, Kigali, Rwanda; 6 Columbia University Medical Center, New York, NY, US 781 Predictors and Outcomes of Incident High Cholesterol in Adults on ART in South Africa Denise Evans 1 ; AlanaT. Brennan 2 ; Faith Moyo 1 ; David Spencer 3 ; Kay Mahomed 3 ; Mhairi Maskew 1 ; Lawrence Long 1 ; Sydney Rosen 2 ; Matt P. Fox 2 1 University of the Witwatersrand, Johannesburg, South Africa; 2 Boston University, Boston, MA, US; 3 Right to Care, Johannesburg, South Africa 782 Metabolic Changes and Second-Line ART in Africa (2LADY/ANRS 12169 Trial) Amandine Cournil 1 ; Assane Diouf 3 ; Sabrina Eymard-Duvernay 1 ; Adrien Sawadogo 2 ; Liliane Ayangma 4 ; Louise Fortes-Deguenonvo 3 ; Jean-Marc Mben 6 ; Eric Delaporte 1 ; Laura Ciaffi 1 ; Sinata Koulla-Shiro 5 1 IRD/UM 1, Montpellier, France; 2 CHU Souro Sanou, Bobo Dioulasso, Burkina Faso; 3 CRCF, Dakar, Senegal; 4 Yaounde Military Hospital, Yaounde, Cameroon; 5 FMSB/University Yaounde 1, Yaounde, Cameroon; 6 ANRS Research Center, Yaounde, Cameroon 2:30 pm– 4:00 pm Aging: Frailty, Telomeres, and mtDNA 783 Frailty and Cause-Specific Hospitalization Among Persons AgingWith HIV and Drug Use Damani A. Piggott 1 ; Abimereki D. Muzaale 1 ; Shruti H. Mehta 1 ; Ryan P.Westergaard 2 ;Todd T. Brown 1 ; KushangV. Patel 3 ; Sean X. Leng 1 ; Gregory D. Kirk 1 1 Johns Hopkins University, Baltimore, MD, US; 2 University of Wisconsin, Madison, WI, US; 3 University of Washington, Seattle, WA, US 784 Association of HIV Viral Load and Shorter Telomere Length Shawn Gogia ; Jue Lin;Yifei Ma; Rebecca Scherzer; Elizabeth Blackburn; Ramin Farzaneh- Far; Steven Deeks; Priscilla Hsue University of California San Francisco, San Francisco, CA, US 785 Novel Mechanisms of Nucleoside Analog Associated Mitochondrial DNA Mutation Kristian Gardner; Patrick F. Chinnery; Brendan A. Payne Newcastle University, Newcastle-upon-Tyne, United Kingdom 786 Balance Confidence Predicts Falls Better Than Physical Function Testing in HIV+Men Todd T. Brown 1 ; Xiuhong Li 2 ; Lisa P. Jacobson 2 ; Jennifer Schrack 2 ; Frank J. Palella 3 ; Lawrence Kingsley 4 ; Joseph B. Margolick 2 ; Adrian Dobs 1 ; Jordan Lake 5 ; Keri N. Althoff 2 MACS 1 Johns Hopkins University School of Medicine, Baltimore, MD, US; 2 Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, US; 3 Northwestern University, Feinberg School of Medicine, Chicago, IL, US; 4 University of Pittsburgh, Pittsburgh, PA, US; 5 University of California Los Angeles, Los Angeles, CA, US TUESDAY, FEBRUARY 24, 2015 Session P-Q6 Poster Session Poster Hall

2:30 pm– 4:00 pm Diabetes and Other Endocrine Disorders 787 Vitamin D Supplementation Does Not Affect Metabolic Changes Seen With ART Initiation Todd T. Brown 1 ; Ellen Chan 2 ; EdgarT. Overton 3 ; PabloTebas 4 ; Kathy Melbourne 5 ; Royce Hardin 6 ; Heather Ribaudo 2 ; MichaelT.Yin 7 ACTG 1 Johns Hopkins University School of Medicine, Baltimore, MD, US; 2 Harvard School of Public Health, Center for Biostatistics in AIDS Research, Boston, MA, US; 3 University of Alabama at Birmingham, Birmingham, AL, US; 4 University of Pennsylvania, Philiadelphia, PA, US; 5 Gilead Sciences, Inc., Foster City, CA, US; 6 Duke University, Durham, NC, US; 7 College of Physicians and Surgeons, Columbia University, New York, NY, US 788 First-Line NRTIs and Risk of New Onset Diabetes in HIV-Infected Adults in Thailand Prakit Riyaten 1 ; Nicolas Salvadori 2 ; PatrineeTraisathit 1 ; Nicole Ngo-Giang-Huong 2 ; Rapeepan Suaysod 2 ; Guttiga Halue 3 ; NarueponYutthakasemsunt 4 ; Apichat Chutanunta 5 ; Jacqueline Capeau 6 ; Gonzague Jourdain 2 1 Chiang Mai University, Chiang Mai, Thailand; 2 Institut de Recherche Pour le Développement UMI 174-PHPT, Chiang Mai, Thailand; 3 Phayao Provincial Hospital, Phayao, Thailand; 4 Nong Khai Hospital, Nong Khai, Thailand; 5 Samutsakhon Hospital, Samutsakhon, Thailand; 6 Sorbonne University, Paris, France 789 Diabetes Mellitus Among HIV-Infected Adults in Care in the United States, 2009–2010 Alfonso C. Hernandez-Romieu Emory University Rollins School of Public Health, Decatur, GA, US 790 Functional Vitamin D Deficiency With Initiation of Tenofovir-Based ART? Evelyn Hsieh 1 ; Liana Fraenkel 1 ;Weibo Xia 2 ;Yang Han 2 ; MichaelTYin 3 ; Karl Insogna 4 ;Ting Zhu 2 ;Taisheng Li 2 1 Yale University School of Medicine, New Haven, CT, US; 2 Peking Union Medical College Hospital, Beijing, China; 3 Columbia University Medical Center, New York, NY, US; 4 Yale University School of Medicine, New Haven, CT, US 791 Determinants of Parathyroid Hormone Levels in HIV-positive Tenofovir- treated Patients with Normal Renal Function Letizia Marinaro ; Andrea Calcagno; Jessica Cusato; Elisabetta Scarvaglieri; Marco Simiele; Maria CristinaTettoni; LauraTrentini; Antonio D’Avolio; Giovanni Di Perri; Stefano Bonora Unit of Infectious Diseases, Turin, Italy 2:30 pm– 4:00 pm Renal Dysfunction: ART and Biomarkers 792 Elevated Tenofovir Exposure via Intensive PK Monitoring Is Associated With Progressive Kidney Function Decline Sanjiv M. Baxi 1 ; Rebecca Scherzer 1 ; Ruth M. Greenblatt 1 ; Howard Minkoff 2 ; Kathryn Anastos 5 ; Mardge H. Cohen 4 ; Mary A.Young 3 ; Monica Gandhi 1 ; Michael G. Shlipak 1 1 University of California San Francisco, San Francisco, CA, US; 2 State University of New York Downstate Medical Center, Brooklyn, NY, US; 3 Georgetown University, Washington, DC, US; 4 John Stroger (formerly Cook County) Hospital, Chicago, IL, US; 5 Montefiore Medical Center, University Hospital for Albert Einstein College of Medicine, Bronx, NY, US 793 Impact of TDF+PI/r on Renal Function in Sub-Saharan Africa : 2LADY/ ANRS 12169 Trial Arsene Hema 1 ; Amandine Cournil 2 ; Laura Ciaffi 2 ; Sabrina Eymard-Duvernay 2 ; Assane Diouf 3 ; Nestor Manga 4 ;Vincent Le Moing 2 ; Jacques Reynes 2 ; Sinata Koulla-Shiro 5 ; Eric Delaporte 2 1 CHU Souro Sanou, Bobo Dioulasso, Burkina Faso; 2 IRD/UM 1, Montpellier, France; 3 Le Centre Régional de Recherche et de Formation à la Prise en Charge Clinique de Fann, Dakar, Senegal; 4 Yaounde Military Hospital, Yaounde, Cameroon; 5 FMSB/University Yaounde 1, Yaounde, Cameroon THURSDAY, FEBRUARY 26, 2015 Session P-Q8 Poster Session Poster Hall

Poster Listings

61

CROI 2015