CROI 2015 Program and Abstracts

Poster Listings

Session P-Q1 Poster Session

Poster Hall

753 sCD163 Correlates With IMT and Macrophages in Aorta and Heart With HIV Infection Joshua A. Walker 1 ; Graham A. Beck 1 ; Andrew D. Miller 2 ;Tricia H. Burdo 1 ; Kenneth C. Williams 1 1 Boston College, Chestnut Hill, MA, US; 2 Cornell University, Ithaca, NY, US 754 Non-Classical Monocytes Predict Progression of Carotid Intima-Media Thickness Dominic C. Chow 1 ; Jamie M. Kagihara 1 ; Guangxiang G. Zhang 1 ; Scott A. Souza 1 ; Brooks I. Mitchell 1 ; Beau K. Nakamoto 1 ; Kalpana J. Kallianpur 1 ; Robert J. Matyas 2 ; Lishomwa C. Ndhlovu 1 ; Cecilia M. Shikuma 1 1 University of Hawaii, Honolulu, HI, US; 2 Kaiser Permanente, Honolulu, HI, US Arjun Sinha 1 ;Yifei Ma 1 ; Rebecca Scherzer 2 ; Courtney Carroll 1 ; Steven Deeks 3 ; Peter Ganz 1 ; Priscilla Hsue 1 1 San Francisco General Hospital, San Francisco, CA, US; 2 San Francisco VA Medical Center, San Francisco, CA, US; 3 University of California San Francisco, San Francisco, CA, US 756 Impaired Cardiac Strain and Biomarkers of Immune Activation in HIV Colleen Hadigan 1 ; Julia Purdy 1 ; DianaThiara 1 ; Louisa Howard 1 ; Chia-Ying Liu 1 ; Fabio Raman 1 ; Sabrina Mangat 1 ; Christopher Sibley 2 ; David Bluemke 1 1 National Institutes of Health (NIH), Bethesda, MD, US; 2 Oregon Health and Sciences University, Portland, OR, US Session P-P7 Poster Session Poster Hall 2:30 pm– 4:00 pm Endothelial Functions and Cerebral Vasoreactivity 757 Role of Angiopoietin 1, Angiopoietin 2, and Endothelial Function in HIV Mark L. Dela Cruz 1 ;Yifei Ma 1 ; Rebecca Scherzer 1 ; AlanWu 2 ; Kristinalisa Maka 1 ; Steven Deeks 1 ; Peter Ganz 1 ; Priscilla Hsue 1 1 University of California San Francisco, San Francisco, CA, US; 2 Blood Systems Research Institute/ University of California San Francisco, San Francisco, CA, US 758 HIV-Infected Persons With Type 2 Diabetes Have Evidence of Endothelial Dysfunction Malene Hove 1 ; Julie C. Gaardbo 3 ; Hedda Hoel 3 ; Lillian Kolte 2 ; AllanVaag 1 ; Jan Gerstoft 1 ; Henrik Ullum 1 ; MariusTroseid 3 ; Susanne D. Poulsen 1 1 Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; 2 Hvidovre Hospital, University Hospital of Copenhagen, Hvidovre, Denmark; 3 Oslo University Hospital, Ullevål, Norway 759 Unique Circulating MicroRNA Profiles and Endothelial Function in HIV Infection Venkata A. Narla 1 ; Nirav Bhakta 2 ; Jane E. Freedman 3 ; KahramanTanriverdi 3 ; Kristinalisa Maka 1 ; Steven Deeks 2 ; Peter Ganz 1 ; Priscilla Hsue 1 1 San Francisco General Hospital, University of California San Francisco, San Francisco, CA, US; 2 University of California San Francisco, San Francisco, CA, US; 3 University of Massachusetts Medical School, Worcester, MA, US 760 Cerebral Vasoreactivity Is Impaired in Virally Suppressed HIV-Infected Individuals Felicia C. Chow 1 ; Claire Mills 1 ; Nerissa Ko 1 ; Courtney Carroll 1 ; Richard Price 1 ; Steven Deeks 1 ; Farzaneh A. Sorond 2 ; PriscillaY. Hsue 1 1 University of California San Francisco, San Francisco, CA, US; 2 Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, US 755 TMAO and HIV-Associated Atherosclerosis

2:30 pm– 4:00 pm Inflammation: Biomarkers and Relationship to Outcomes 761 IL-6 Is a Stronger Predictor of Clinical Events Than hsCRP or D-Dimer in HIV Disease Álvaro H. Borges 1 ; Jemma L. O’Connor 2 ; Andrew N. Phillips 2 ; James D. Neaton 3 ; Birgit Grund 4 ; Jacqueline Neuhaus 3 ; MichaelVjecha 7 ; Alexandra Calmy 5 ; Kersten K. Koelsch 6 ; Jens D. Lundgren 1 INSIGHT SMART and ESPRIT Study Groups 1 Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; 2 University College London, London, United Kingdom; 3 University of Minnesota, Minneapolis, MN, US; 4 University of Minnesota, Minneapolis, MN, US; 5 Geneva University Hospitals, Geneva, Switzerland; 6 University of New South Wales, Sydney, Australia; 7 Veterans Affairs Medical Center, Washington, DC, US 762 Persistent Inflammation on ART Is AssociatedWith Poor Nutritional Recovery in Zambia George Praygod 2 ; Meridith Blevins 1 ; SusannahWoodd 3 ; Andrea Rehman 3 ; Jeremiah Kidola 2 ; Henrik Friis 4 ; Paul Kelly 5 ; Douglas Heimburger 1 ; Suzanne Filteau 3 ; John Koethe 1 1 Vanderbilt University, Nashville, TN, US; 2 National Institute of Medical Research, Mwanza, United Republic of Tanzania; 3 London School of Hygiene & Tropical Medicine, London, United Kingdom; 4 University of Copenhagen, Copenhagen, Denmark; 5 University Teaching Hospital, Lusaka, Zambia 763 Smoking and Obesity May Partially Explain the Inflammation and Morbidity Association Supriya Krishnan 1 ; Ronald Bosch 1 ; Benigno Rodriguez 2 ; PeterW. Hunt 3 ; Cara C.Wilson 4 ; Steven Deeks 3 ; Michael M Lederman 2 ; Alan Landay 5 ; Carey Lumeng 6 ; AllanTenorio 7 1 Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA, US; 2 Division of Infectious Diseases and HIV Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, US; 3 Positive Health Program, Dept of Medicine, San Francisco General Hospital, San Francisco, CA, US; 4 Division of Infectious Diseases, Univ of Colorado Hospital, Aurora, CO, US; 5 Department of Immunology and Microbiology, Rush Univ Medical Center, Chicago, IL, US; 6 Univ of Michigan Medical School, Department of Pediatrics, Ann Arbor, MI, US; 7 Department of Medicine, Rush University Medical Center, Chicago, IL, US 764 Infectious and Noninfectious Multimorbidity Among HIV Clinic Clients in the African Cohort Study Julie Ake 1 ; Jonah Maswai 2 ; Francis Kiweewa 3 ; Lucas Maganga 4 ; Milton Omondi 5 ; Babajide Keshinro 6 ; Lindsay Hughes 1 ;Victor G.Valcour 7 ; Christina Polyak 1 RV 329 AFRICOS StudyTeam 1 US Military HIV Research Program, Bethesda, MD, US; 2 KEMRI/Walter Reed Project, Kericho, Kenya; 3 Makerere University Walter Reed Project, Kampala, Uganda; 4 Mbeya Medical Research Centre, Mbeya, United Republic of Tanzania; 5 KEMRI/Walter Reed Project, Kisumu, Kenya; 6 Walter Reed Program - Nigeria, Abuja, Nigeria; 7 University of California San Francisco (UCSF), San Francisco, CA, US 2:30 pm– 4:00 pm Bone Metabolism and ART: Mechanisms and Outcomes 765 Bone Metabolism and Tenofovir: Evidence of Direct Effect on Calcium- Sensing Receptor Paolo Bonfanti 2 ; Caterina Brasacchio 3 ; Chiara Molteni 2 ; Barbara Menzaghi 1 ; Laura Soldati 3 ; Tiziana Quirino 1 ; Stefano Mora 4 1 Busto Arsizio Hospital, Busto Arsizio, Italy; 2 A. Manzoni Lecco Hospital, Lecco, Italy; 3 Department of Health Sciences, University of Milan, Milan, Italy; 4 San Raffaele Scientific Institute, Milan, Italy 766 Bone Turnover on DRV/r + Either RAL or TDF/FTC as First-Line ART: NEAT 001 / ANRS 143 Jose I Bernardino 1 ; Amanda Mocroft 2 ; Laura Richert 3 ; Abdel Babiker 4 ; Antonio Buño 1 ; Antonella Castagna 5 ; Pierre-Marie Girard 6 ; Genevieve Chene 3 ; Jose R Arribas 1 ; François Raffi 7 1 Hospital Universitario La Paz. IdiPAZ, Madrid, Spain; 2 University College London, London, United Kingdom; 3 University of Bordeaux, Bordeaux, France; 4 MRC Clinical Trials Unit at University College London, London, United Kingdom; 5 San Raffaele Scientific Institute, Milan, Italy; 6 Hospital St Antoine and Inserm, Paris, France; 7 Université Nantes, Nantes, France Session P-Q2 Poster Session

Poster Listings

Poster Hall

59

CROI 2015