CROI 2020 Program and Conference Information

Oral Sessions

25 STRUCTURAL BASIS OF SECOND-GENERATIONHIV INTEGRASE INHIBITOR ACTION ANDVIRUS ESCAPE Nicola Cook, Wen Li, Dénes Berta, Magd Badaoui, Allison Ballandras-Colas, Andrea Nans, Abhay Kotecha, Edina Rosta, Alan N. Engelman, Peter Cherepanov 26 THE CHROMATIN LANDSCAPE AT THE HIV-1 INTEGRATION SITE DETERMINES VIRAL EXPRESSION Gerlinde Vansant, Julie Janssens, Heng-Chang Chen, Eduard Zorita, Frauke Christ, Guillaume Filion, Zeger Debyser Oral Abstract O-02 NOVEL ASSESSMENTS OF CENTRAL NERVOUS SYSTEM PATHOGENESIS Room 304-306 10:00 AM - 12:00 PM Oral Abstract Moderators Jaime H. Vera Rojas , Brighton and Sussex Medical School, Brighton, United Kingdom Sara Gianella , University of California San Diego, La Jolla, CA, USA 27 SINGLE-CELL GENOMIC ANALYSIS OF BLOOD AND CSF T CELLS IN HIV+AND HIV– ADULTS Shelli Farhadian , Ofir Lindenbaum, Jun Zhao, Rolando Garcia-Milian, Jennifer Chiarella, Michelle Chintanaphol, Rachela Calvi, Yuval Kluger, Serena S. Spudich GREATER BURDEN OF INTRACRANIAL ARTERIAL-WALL ENHANCEMENT IN PERSONS LIVINGWITHHIV Felicia C. Chow , Andrew Callen, Victor Arechiga, David Saloner, Jared Narvid, Priscilla Hsue 29 PET IMAGING OF SYNAPTIC DENSITY INHIV: PRELIMINARY FINDINGS FROMA PILOT STUDY 11:30 11:45 10:00 10:15 10:30 28 Julian Weiss , Rachela Calvi, Mika Naganawa, Takuya Toyonaga, Shelli Farhadian, Michelle Chintanaphol, Jennifer Chiarella, Ming-Qiang Zheng, Jim Ropchan, Yiyun Huang, Richard Carson, Serena S. Spudich HIV-INFECTEDMACROPHAGES EVADE NK CELL-MEDIATED KILLINGWHILE DRIVING INFLAMMATION Kiera L. Clayton , Heather Stuart, Geetha H. Mylvaganam, Alonso Villasmil Ocando, Marcela Maus, Bruce D. Walker 31 HIV DNA DETECTED IN IMMUNE CELL SUBSETS IN CSF DURING ART 10:45 11:00 30 Shelli Farhadian, Joshua C. Cyktor , Asma Naqvi, Michael J. Corley, Jennifer Chiarella, Rachela Calvi, Michelle Chintanaphol, Geoffrey Lyon, Diane Trotta, John W. Mellors, Serena S. Spudich EFFECTS OF HIV AND AGING ON RESTING-STATE NETWORKS Patrick Luckett , Anupama Melam, Sarah A. Cooley, Joshua Shimony, Beau Ances MYELIN CONTENT IS ELEVATED INVIROLOGICALLY UNSUPPRESSED PEOPLE LIVINGWITHHIV Dimitre Tomov , Sarah A. Cooley, Casey Bowen, Jeremy Strain, Beau Ances 32 33 11:15 11:30

Oral Sessions • Monday

CROI 2020 35