CROI 2017 Program and Information

Program and Agenda

362 PREVALENCE OF NEUROCOGNITIVE DISORDERS IN AWELL- TREATED AND AGING SWISS HIV-COHORT Melanie Metral 1 , Isabella Locatelli 1 , Peter Brugger 2 , Klemens Gutbrod 3 , Ursula Kunze 4 , Isaure Nadin 5 , Marc Schwind 6 , Riccardo Pignatti 7 , Matthias Cavassini 1 , Renaud Du Pasquier 1 1 Univ of Lausanne, Lausanne, Switzerland, 2 Univ Hosp of Zürich, Zürich, Switzerland, 3 Univ Hosp of Bern, Bern, Switzerland, 4 Felix Platter Hosp, Basel, Switzerland, 5 Univ Hosps of Geneva, Geneva, Switzerland, 6 Klinik für Neuro, St. Gallen, Switzerland, 7 Servizio di Malattie Infettive, Lugano, Switzerland Poster P-G5 ANTIRETROVIRAL PHARMACOKINETICS: SPECIAL PROBLEMS AND POPULATIONS Poster Hall - 4 EF 2:30 PM - 4:00 PM 428 EFFECT OF SORBITOL ON3TC PK AFTER ADMINISTRATION OF LAMIVUDINE SOLUTION IN ADULTS Kimberly K. Adkison 1 , Cynthia McCoig 2 , Allen Wolstenholme 3 , Yu Lou 4 , Zhiping Zhang 4 , Amy Eld 3 , Katy Hayward 5 , Mark Shaefer 1 1 ViiV Hlthcare, Rsr Triangle Park, NC, USA, 2 ViiV Hlthcare, Tres Cantos, Madrid, Spain, 3 GlaxoSmithKline, Collville, PA, USA, 4 PAREXEL Intl, Durham, NC, USA, 5 ViiV Hlthcare, Brentford, UK 429 CRUSHING OF DOLUTEGRAVIR COMBINATION TABLETS INCREASES DOLUTEGRAVIR EXPOSURE Marieke Roskam-Kwint 1 , Pauline Bollen 1 , Angela Colbers 1 , Marjolijn Duisenberg-van Essenberg 2 , Veroniek Harbers 1 , Reinout van Crevel 1 , David M. Burger 1 1 Radboud Univ Med Cntr, Nijmegen, Netherlands, 2 Elisabeth–TweeSteden Ziekenhuis, Tilburg, Netherlands 430 EFFECT OF SEVERE RENAL IMPAIRMENT ON DORAVIRINE PHARMACOKINETICS Wendy Ankrom 1 , Kelly Yee 1 , Rosa Sanchez 1 , Adedayo Adedoyin 1 , Li Fan 1 , Thomas Marbury 2 , Richard A. Preston 3 , Sauzanne Khalilieh 1 , Marian Iwamoto 1 1 Merck & Co, Inc, Kenilworth, NJ, USA, 2 Orlando Clinical Rsr Cntr, Orlando, FL, USA, 3 Univ of Miami, Miami, FL, USA 431 HIGHER PLASMA LEVELS ANDMORE SIDE EFFECTS IN ELDERLY DARUNAVIR-TREATED PATIENTS Erika Ahlgren 1 , Arvid Edén 1 , Jaran Eriksen 2 , Staffan Nilsson 3 , Carl Johan Treutiger 2 , Anders Thalme 4 , Anders Blaxhult 5 , Åsa Mellgren 6 , Magnus Gisslén 1 , Lars-Magnus Andersson 1 1 Univ of Gothenburg, Gothenburg, Sweden, 2 Karolinska Inst, Stockholm, Sweden, 3 Chalmers Univ of Tech, Gothenburg, Sweden, 4 Karolinska Univ Hosp, Stockholm, Sweden, 5 Sodersjukhuset, Stockholm, Sweden, 6 South Älvsborgs Hosp, Borås, Sweden 432 PHARMACOKINETICS OF DOLUTEGRAVIR IN PEOPLE LIVING WITHHIV OVER THE AGE OF 60 Emilie Elliot 1 , Xinzhu Wang 2 , Nicole Pagani 1 , Alison Jenkin 1 , Jaime Vera- Rojas 3 , Isaac Day-Weber 2 , Graeme Moyle 4 , Myra McClure 2 , Marta Boffito 1 1 St. Stephen’s AIDS Trust–Chelsea and Westminster Hosp, London, UK, 2 Imperial Coll, London, UK, 3 Brighton and Sussex Med Sch, Brighton, UK, 4 Chelsea and Westminster Hosp, London, UK

Poster Sessions • Thursday

CROI 2017 179