CROI 2017 Program and Information

Program and Agenda

287 PRE-ART TUBERCULOSIS AND TB-IRIS AFFECT THE HIV-1 RESERVOIR Camille Lange 1 , Maura Manion 2 , Gregg Roby 3 , Rob Gorelick 4 , Virginia Sheikh 5 , Joseph Adelsberger 6 , Frank Maldarelli 1 , Irini Sereti 2

1 NCI, Frederick, MD, USA, 2 NIAID, Bethesda, MD, USA, 3 NIH, Rockville, MD, USA, 4 AIDS and Cancer Virus Prog, Frederick, MD, USA, 5 FDA, Silver Spring, MD, USA, 6 Leidos Biomed Rsr, Inc, Frederick, MD, USA

Poster P-E4 HIV PERSISTENCE: SEND IN THE CLONES Poster Hall - 4 EF 292 CLONAL EXPANSION OF GENOME-INTACT HIV-1 IN FUNCTIONALLY POLARIZED T-CELL SUBSETS

2:30 PM - 4:00 PM

Guinevere Q. Lee 1 , Nina Orlova 1 , Erik Serrao 2 , Xiaoming Sun 1 , Navin F. Chowdhury 1 , Eric Rosenberg 3 , Alan N. Engelman 2 , Xu G. Yu 1 , Mathias Lichterfeld 4

1 Ragon Inst of MGH, MIT and Harvard, Cambridge, MA, USA, 2 Dana-Farber Cancer Inst, Boston, MA, USA, 3 Massachusetts General Hosp, Boston, MA, USA, 4 Brigham and Women's Hosp, Boston, MA, USA 293 INTACT PROVIRUSES ARE UNEQUALLY DISTRIBUTED IN T CELL SUBSETS DURING ART Bonnie Hiener 1 , Bethany A. Horsburgh 1 , John-Sebastian Eden 2 , Kirston Barton 1 , Eunok Lee 1 , Steven G. Deeks 3 , Jeffery Milush 3 , Nicolas Chomont 4 , Rémi Fromentin 4 , Sarah Palmer 1 1 The Westmead Inst for Med Rsr, Westmead, Australia, 2 The Univ of Sydney, Sydney, Australia, 3 Univ of California San Francisco, San Francisco, CA, USA, 4 Univ de Montréal, Montreal, QC, Canada 294 A SMALL FRACTION OF PROVIRUSES IN EXPANDED CLONES EXPRESS UNSPLICED HIV RNA INVIVO AndrewMusick 1 , Jonathan Spindler 1 , Brandon Keele 2 , Michael J. Bale 1 , Wei Shao 2 , Ann Wiegand 1 , John Mellors 3 , John Coffin 4 , Frank Maldarelli 1 , Mary F. Kearney 1 1 NCI, Frederick, MD, USA, 2 Leidos Biomed, Inc, Frederick, MD, USA, 3 Univ of Pittsburgh, Pittsburgh, PA, USA, 4 Tufts Univ, Boston, MA, USA 295 PROLIFERATION OF CD4+T CELLS CONTAINING REPLICATION- COMPETENT HIV-1 Zheng Wang , Ya-Chi Ho, Janet Siliciano, Robert Siliciano Johns Hopkins Univ, Baltimore, MD, USA 296 CYTOTOXIC T LYMPHOCYTESMAY SHAPE THE HIV-1 PROVIRAL LANDSCAPE R. Brad Jones 1 , Mihaela Pertea 2 , Katherine Bruner 2 , Ross Pollack 2 , Adam Capoferri 2 , Robert Siliciano 2 , Ya-Chi Ho 2 1 The George Washington Univ, Washington, DC, USA, 2 The Johns Hopkins Univ, Baltimore, MD, USA 297 DYNAMICS OF HIV CLONAL EXPANSION AND PERSISTENCE DURING ART Elizabeth M Anderson 1 , Shawn Hill 1 , Jennifer Bell 1 , Francesco R. Simonetti 2 , Cathy Rehm 3 , Sara Jones 4 , Rob Gorelick 4 , John Coffin 5 , Frank Maldarelli 1 1 NCI, Frederick, MD, USA, 2 The Johns Hopkins Univ, Baltimore, MD, USA, 3 NIAID, Bethesda, MD, USA, 4 Leidos Biomed Rsr, Inc, Frederick, MD, USA, 5 Tufts Univ, Boston, MA, USA

Poster Sessions • Thursday

CROI 2017 173