CROI 2017 Program and Information

Program and Agenda

Poster Sessions • Wednesday Poster P-G4 EXPOSURE-RESPONSE RELATIONSHIPS OF ANTIRETROVIRAL DRUGS Poster Hall - 4 EF 2:30 PM - 4:00 PM 423 AN INVITRO–IN SILICO STUDY OF REDUCED-DOSE EFAVIRENZ INTERACTIONWITH LEVONORGESTREL Owain Roberts 1 , Paul Curley 1 , Rajith Kumar Reddy Rajoli 1 , Darren M. Moss 1 , Mohammed Lamorde 3 , Andrew Owen 1 , Kimberly K. Scarsi 3 , Marco Siccardi 1 1 Univ of Liverpool, Liverpool, UK, 2 Infectious Diseases Inst Ltd, Kampala, Uganda, 3 Univ of Nebraska, Omaha, NE, USA 424 PHARMACOKINETICS, SAFETY & EFFICACY OF E/C/F/TAF INHIV- INFECTED CHILDREN (6-12 YRS) Aditya Gaur 1 , Eva Natukunda 2 , Pope Kosalarksa 3 , Jag Batra 4 , Natella Rakhmanina 5 , Amy Coluci 6 , Yongwu Shao 6 , Heather Zhang 6 , Cheryl Pikora 6 , Martin Rhee 6 1 St. Jude Children’s Rsr Hosp, Memphis, TN, USA, 2 Joint Clinical Rsr Cntr, Kampala, Uganda, 3 Khon Kaen Univ, Khon Kaen, Thailand, 4 Miller Children’s Hosp, Long Beach, CA, USA, 5 Children's Rsr Inst–Children’s Natl Med Cntr, Washington, DC, USA, 6 Gilead Scis, Inc, Foster City, CA, USA 410 INCREASED DOLUTEGRAVIR EXPOSURE INHIV PATIENTS SWITCHED FROMRITONAVIR TO COBICISTAT Cristina Gervasoni , Agostino Riva, Amedeo Capetti, Valeria Cozzi, Giuliano Rizzardini, Massimo Galli, Emilio Clementi, Dario Cattaneo Luigi Sacco Univ Hosp, Milan, Italy 411 EFFECT OF COBICISTAT ON TENOFOVIR PLASMA CONCENTRATION: A CROSS-SECTIONAL STUDY Cristina Gervasoni 1 , Davide Minisci 1 , Sara Baldelli 1 , Cristina Mazzali 2 , Andrea Giacomelli 1 , Laura Milazzo 1 , Paola Meraviglia 1 , Emilio Clementi 1 , Massimo Galli 1 , Dario Cattaneo 1 1 Luigi Sacco Univ Hosp, Milano, Italy, 2 Politecnico di Milano, Italy, Milano, Italy 412 MULTIPLE-DOSE TREATMENTWITH RITONAVIR INCREASES THE EXPOSURE OF DORAVIRINE Sauzanne Khalilieh 1 , Matt Anderson 1 , Tine Laethem 2 , Kelly Yee 1 , Rosa Sanchez 1 , Li Fan 1 , Monali Sura 1 , Luc Van Bortel 3 , Greit Van Lancker 3 , Marian Iwamoto 1 1 Merck & Co, Inc, Kenilworth, NJ, USA, 2 MSD Belgium, Brussels, Belgium, 3 Ghent Univ Hosp, Ghent, Belgium 413 GLECAPREVIR AND PIBRENTASVIR INTERACTIONSWITH COMBINATION ANTIRETROVIRAL REGIMENS Matthew P. Kosloski , Sandeep Dutta, Rolando M. Viani, Xin Qi, Roger Trinh, Andrew Campbell, Wei Liu AbbVie, North Chicago, IL, USA 414 EFFECT OF LOW-DOSEMETHOTREXATE ON THE PHARMACOKINETICS OF TENOFOVIR David Gingich 1 , Heather Ribaudo 2 , Amy Kantor 2 , James H. Stein 3 , Judith S. Currier 4 , Priscilla Hsue 1 , Francesca Aweeka 1 1 Univ of California San Francisco, San Francisco, CA, USA, 2 Harvard Univ, Boston, MA, USA, 3 Univ of Wisconsin, Madison, WI, USA, 4 Univ of California Los Angeles, Los Angeles, CA, USA

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