CROI 2017 Program and Information

Program and Agenda

Poster P-D4 CD8 T CELLS: WHERE AND HOW THEY KILL Poster Hall - 4 EF 2:30 PM - 4:00 PM 266 LYMPHNODE HIV-SPECIFIC CXCR5+CTLs ARE ASSOCIATEDWITH ENHANCEDVIRAL CONTROL Zaza Ndhlovu 1 , Funsho Ogunshola 2 , Omolara Baiyegunhi 2 , Nikoshia Mewalal 2 , Amber Moodley 2 , Krista Dong 1 , Thumbi Ndung’u 2 , Bruce D. Walker 1 1 Ragon Inst of MGH, MIT and Harvard, Cambridge, MA, USA, 2 Univ of KwaZulu Natal, Durban, South Africa 267 RESIDENTMEMORY CD8+T CELLS FORMTHE FRONT-LINE DEFENSE INHIV-INFECTED LYMPHNODES Marcus Buggert 1 , Lalit Beura 2 , Son Nguyen 1 , David Canaday 3 , Ali Naji 4 , Constantinos Petrovas 5 , Gustavo Reyes-Terán 6 , Steven G. Deeks 7 , David Masopust 2 , Michael R. Betts 1 1 Univ of Pennsylvania, Philadelphia, PA, USA, 2 Univ of Minnesota, Minneapolis, MN, USA, 3 Case Western Reserve Univ, Cleveland, OH, USA, 4 Hosp of the Univ of Pennsylvania, Philadelphia, PA, USA, 5 NIH, Bethesda, MD, USA, 6 Rsr Cntr in Infectious Diseases, Mexico City, Mexico, 7 Univ of California San Francisco, San Francisco, CA, USA 268 HIV-1 ESCAPE FROMCD8+CYTOTOXIC T-LYMPHOCYTES DEFINED AT CLONAL RESOLUTION Aleksandr Gorin , Yushen Du, Ren Sun, Otto Yang Univ of California Los Angeles, Los Angeles, CA, USA 269 INVESTIGATING THE ROLE OF TCR STRUCTURE IN FUNCTIONAL ACTIVITY OF HIV-SPECIFIC CTLs Nina C. Flerin 1 , Tynisha Glover 1 , Huabiao Chen 2 , Jianhua Zheng 1 , Harris Goldstein 1 1 Albert Einstein Coll of Med, Bronx, NY, USA, 2 Ragon Inst of Massachusetts General Hosp, Cambridge, MA, USA 270 HIV-SPECIFIC CD8 T CELLS IN PERSONS TREATED IN FIEBIG I ACUTE INFECTIONWHO STOP ART Hiroshi Takata 1 , Donn Colby 2 , Eugene Kroon 2 , Suteeraporn Pinyakorn 1 , Nelson L. Michael 3 , Merlin L. Robb 1 , Jintana Intasan 2 , Jintanat Ananworanich 4 , Lydie Trautmann 1 , for the RV411 and RV254/SEARCH010 Study Groups 1 Walter Reed Army Inst of Rsr, Silver Spring, MD, USA, 2 SEARCH, The Thai Red Cross AIDS Rsr Cntr, Bangkok, Thailand, 3 Walter Reed Army Inst of Rsr, Silver Spring, MD, USA, 4 US Military HIV Rsr Prog, Silver Springs, MD, USA 271 EARLY CART OF HIV-1 INFECTED SUBJECTS PRESERVES ANTIVIRAL FUNCTION OF CD8+T CELLS Miriam Rosas Umbert 1 , Beatriz Mothe 2 , Gemma Hancock 3 , Hongbing Yang 3 , Christian Manzardo 4 , Josep Coll 1 , Christian Brander 1 , Lucy Dorrell 3 1 IrsiCaixa AIDS Rsr Inst, Badalona, Spain, 2 Hosp Germans Trias i Pujol, Badalona, Spain, 3 Univ of Oxford, Oxford, UK, 4 Univ of Barcelona, Barcelona, Spain 272 ROLE OF CTL IN PEDIATRIC HIV CURE STRATEGIES FOLLOWING EARLYWIDESPREADVIRAL ESCAPE Ellen M. Leitman 1 , Christina F. Thobakgale 2 , M. Azim Ansari 1 , Jayna Raghwani 1 , Emily Adland 1 , Oliver Pybus 1 , Paul Kellam 3 , Philippa C. Matthews 4 , Astrid Gall 5 , Philip J. Goulder 1 1 Univ of Oxford, Oxford, UK, 2 Univ of KwaZulu-Natal, Durban, South Africa, 3 Kymab Ltd, Babraham Rsr Campus, Cambridge, UK, 4 Oxford Univ Hosps NGS Trust, John Radcliffe Hosp, Oxford, UK, 5 Wellcome Trust Sanger Inst, Hinxton, UK

Poster Sessions • Wednesday

CROI 2017 126