CROI 2015 Program and Abstracts

Poster Listings

TUESDAY, FEBRUARY 24, 2015 Session P-U5 Poster Session

929 High Prevalence of Dyslipidemia and Insulin Resistance in African Children on ART Steve Innes 1 ; Kameelah L. Abdullah 2 ; Richard Haubrich 2 ; Sara Browne 2 ; Mark F. Cotton 1 1 Stellenbosch University, Cape Town, South Africa; 2 University of California San Diego, San Deigo, CA, US 930 Growth and Lipid Profiles in a South African Cohort of HIV + Children and HIV - Controls Sarah Ramteke 1 ; Stephanie Shiau 1 ; Marc Foca 1 ; Renate Strehlau 2 ; Francoise Pinillos 2 ; Faeezah Patel 2 ; AvyViolari 3 ; Afaaf Liberty 3 ; Stephen M. Arpadi 1 ; Louise Kuhn 1 1 Columbia University, New York, NY, US; 2 University of the Witwatersrand, Johannesburg, South Africa; 3 University of Witwatersrand, Johannesburg, South Africa Session P-U7 Poster Session Poster Hall 2:30 pm– 4:00 pm Complications of HIV and ART: Bones, Brains, and Kidneys 931 Vitamin D Status and Bone Outcomes in Perinatally HIV-Infected Children Denise L. Jacobson 1 ; Mitchell Geffner 2 ; Charles B. Stephensen 3 ; Rohan Hazra 4 ; Kunjal Patel 8 ;Tracie L. Miller 5 ; Russell B.Van Dyke 6 ; Angela Ellis 9 ; Linda A. DiMeglio 7 For the Pediatric HIV/AIDS Cohort Study 1 Harvard School of Public Health, Center for Biostatistics in AIDS Research, Boston, MA, US; 2 Children’s Hospital Los Angeles, Keck School of Medicine, Los Angeles, CA, US; 3 USDA, Davis, CA, US; 4 Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, US; 5 University of Miami, Miami, FL, US; 6 Tulane University School of Medicine, New Orleans, LA, US; 7 Indiana University, School of Medicine, Indianapolis, IN, US; 8 Harvard School of Public Health, Boston, MA, US; 9 Frontier Science and Research Foundation, Amherst, NY, US 932 Bone Quality by Ultrasonometry in South African HIV+ Children and HIV- Controls Stephen M. Arpadi 1 ; Stephanie Shiau 1 ; Renate Strehlau 2 ; Francoise Pinillos 2 ; Faeezah Patel 2 ; Louise Kuhn 1 ; Ashraf Coovadia 2 ; Sarah Ramteke 1 ; Jonathan Kaufman 3 ; MichaelT.Yin 1 1 Columbia University, New York, NY, US; 2 University of the Witwatersrand, Johannesburg, South Africa; 3 Mount Sinai School of Medicine, New York, NY, US 933 APOL1 Gene Variants and Chronic Kidney Disease in Perinatally HIV- Infected Youth Murli Purswani 1 ; Kunjal Patel 2 ; CherylWinkler 3 ; Stephen Spector 4 ; Rohan Hazra 5 ; George Seage 2 ; Lynne Mofenson 5 ; Gwendolyn Scott 6 ; RussellVan Dyke 7 ; Jeffrey Kopp 8 For the Pediatric HIV/AIDS Cohort Study (PHACS) 1 Albert Einstein College of Medicine, Bronx, NY, US; 2 Harvard School of Public Health, Boston, MA, US; 3 National Cancer Institute (NCI), Bethesda, MD, US; 4 University of California San Diego, San Diego, CA, US; 5 Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, US; 6 University of Miami, Miami, FL, US; 7 Tulane University, New Orleans, LA, US; 8 National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, US 934 Cystatin C Is a Marker for Both Inflammation and Renal Function in HIV+ Children Àngela Deyà-Martínez 1 ; Clàudia Fortuny 1 ; Pere Soler-Palacín 2 ; Olaf Neth 3 ; Emilia Sánchez 4 ; Andrea Martín-Nalda 2 ; Lola Falcón-Neyra 3 ; AnnaVila 1 ; AnnaValls 1 ; Antoni Noguera-Julian 1 1 Hospital Sant Joan de Déu, Esplugues, Spain; 2 Hospital Vall d’Hebrón, Barcelona, Spain; 3 Hospital Virgén del Rocío, Sevilla, Spain; 4 Universitat Ramon Llull, BArcelona, Spain 935 Cognitive Performance and Intracerebral Findings in Perinatally HIV- Infected Children Sophie Cohen 1 ; MatthanW. Caan 2 ; Jacqueline A. ter Stege 3 ; Henriette J. Scherpbier 1 ;Taco W. Kuijpers 1 ; Peter Reiss 2 ; Gert J. Geurtsen 2 ; Charles B. Majoie 2 ; Ben Schmand 2 ; Dasja Pajkrt 1 1 Emma Children’s Hospital AMC, Amsterdam, Netherlands; 2 Academic Medical Center University of Amsterdam, Amsterdam, Netherlands; 3 Emma Children’s Hospital, Amsterdam, Netherlands 936 Executive Functions Among Perinatally HIV-Exposed and HIV-Infected Youth Sharon L. Nichols 1 ; Miriam Chernoff 2 ; Kathleen M. Malee 3 ; Patricia A. Sirois 4 ; Paige L. Williams 2 ; Betsy L. Kammerer 5 the Memory SubstudyTeam of the Pediatric HIV/AIDS Cohort Study (PHACS) 1 University of California, San Diego, La Jolla, CA, US; 2 Harvard School of Public Health, Center for Biostatistics in AIDS Research, Boston, MA, US; 3 Northwestern University Feinberg School of Medicine, Chicago, IL, US; 4 Tulane University School of Medicine, New Orleans, LA, US; 5 Children’s Hospital Boston, Boston, MA, US

Poster Hall

2:30 pm– 4:00 pm Determinants of Disease Progression in Children 921 Impact of Sex Differences on Disease Outcome in Pediatric HIV in South Africa Masahiko Mori 1 ; Emily Adland 1 ; Alice Swordy 1 ; Maximilian Muenchhoff 1 ; Nora Lavandier 1 ; Jacob Hurst 1 ;Thumbi Ndung’u 2 ; Andy Prendergast 3 ; Philip J. Goulder 1 ; Pieter Jooste 4 1 University of Oxford, Oxford, United Kingdom; 2 University of KwaZulu-Natal, Durban, South Africa; 3 Queen Mary University of London, London, United Kingdom; 4 Kimberley Hospital, Durban, South Africa 922 CD31 Expression on CD4 Cells Predicts Clinical Course of HIV in a Perinatally HIV-Infected Cohort Ramia Zakhour 1 ; Gilhen Rodriguez 2 ; Cynthia Bell 2 ; Guenet Degaffe 2 ; Laura Benjamins 2 ; Gabriela DelBianco 2 ; Elizabeth Donnachie 2 ;Tran Dat 2 ; Gloria P. Heresi 2 ; James R. Murphy 2 1 University of Texas, Houston, TX, US; 2 UTHealth Medical School, Houston, TX, US 923 Premature Aging and Immune Senescence in HIV-1-Infected Children Ketty Gianesin 1 ; Antoni Noguera-Julian 2 ; Marisa Zanchetta 3 ; Osvalda Rampon 1 ; Clàudia Fortuny 2 ; Mireia Camós 2 ; Carlo Giaquinto 1 ; Anita De Rossi 1 1 University of Padova, Padova, Italy; 2 Hospital Sant Joan de Déu-Universitat de Barcelona, Barcelona, Spain; 3 Istituto Oncologico Veneto–IRCCS, Padova, Italy 924 KIR/HLA Alleles Alter CD4 + Lymphocyte Count and Viral Load in HIV- Infected Children Kumud Singh 1 ; Min Qin 2 ; Sean Brummel 2 ; Konstantia Angelidou 2 ; RodneyTrout 1 ;Terrence Fenton 2 ; Stephen Spector 1 1 University of California San Diego, La Jolla, CA, US; 2 Harvard School of Public Health, Boston, MA, US 2:30 pm– 4:00 pm Complications of HIV and ART: Pulmonary and Cardiovascular Outcomes 925 Arterial Stiffness in HIV+ Youth and Associations With HIV-Related Variables Allison R. Eckard 1 ; Julia C. Rosebush 1 ; Mary Ann O’Riordan 2 ; ChristopherT. Longenecker 2 ; BridgetWynn 1 ; Monika Uribe Leitz 1 ; Danielle Labbato 2 ; Norma Storer 2 ; Bruce Kinley 2 ; Grace A. McComsey 2 1 Emory University School of Medicine, Atlanta, GA, US; 2 Case Western Reserve University, Cleveland, OH, US 926 Does Early ART Normalize Pulse-Wave Velocity in Children? Evidence From CHER Cohort Steve Innes 1 ; Zukiswa Magogotya 1 ; Philip Herbst 1 ; Mark F. Cotton 1 ; Barbara Laughton 1 ; Sara Browne 2 ; Richard Haubrich 2 1 Stellenbosch University, Cape Town, South Africa; 2 University of California San Diego, San Deigo, CA, US 927 The Impact of HIV and ART on Markers of Inflammation, Vascular Injury and Disordered Thrombogenesis in Children Julia M. Kenny 1 ; SarahWalker 1 ; Adrian Cook 1 ;Victor Musiime 2 ; PriscillaWavamunno 2 ; Florence Odongo 2 ; Grace Mirembe 2 ; Dorica Masaku 3 ; Diana M. Gibb 1 ; Nigel J. Klein 1 1 University College London, London, United Kingdom; 2 Joint Clinical Resarch Centre, Kampala, Uganda; 3 University Teaching Hospital, Lusaka, Zambia 928 T-Cell Activation and E-Selectin AssociatedWith Coronary Plaque in HIV- Infected Youth Julia B. Purdy ; Aylin Unsal; Khaled Abd-Elmoniem; Adam Rupert; Joseph A. Kovacs; Rohan Hazra; Ahmed Gharib; Colleen Hadigan National Institutes of Health, Bethesda, MD, US THURSDAY, FEBRUARY 26, 2015 Session P-U6 Poster Session Poster Hall

Poster Listings

71

CROI 2015