CROI 2015 Program and Abstracts

Poster Listings

Session P-R3 Poster Session

Poster Hall

Session P-R4 Poster Session

Poster Hall

2:30 pm– 4:00 pm TB Diagnostic Challenges 822 Unsuspected Prevalent TB among HIV-Infected Pregnant Women, South Africa Jennifer D. Hoffmann 1 ; Silvia E. Cohn 1 ; Fildah Mashabela 2 ; ZiyaadWaja 2 ; Christopher J. Hoffmann 1 ; Neil Martinson 2 ; Richard E. Chaisson 1 Tshepiso StudyTeam 1 Johns Hopkins University School of Medicine, Baltimore, MD, US; 2 Perinatal HIV Research Unit (PHRU), Johannesburg, South Africa 823 Evaluation of WHO 4-Symptom Tool to Rule Out TB: Data From the XPHACTOR Study Yasmeen Hanifa 1 ; Katherine Fielding 1 ;Violet Chihota 2 ; Nontobeko Ndlovu 2 ; Alan Karstaedt 3 ; Lungiswa Adonis 4 ; Linda Erasmus 5 ; Mark Nicol 5 ; Gavin Churchyard 2 ; Alison Grant 1 1 London School of Hygiene & Tropical Medicine, London, United Kingdom; 2 Aurum Institute for Health Research, Johannesburg, South Africa; 3 Chris Hani Baragwanath Hospital, Johannesburg, South Africa; 4 Mamelodi Hospital, Pretoria, South Africa; 5 National Health Laboratory Service, Johannesburg, South Africa 824 Xpert MTB/RIF Versus AFB Smear to Determine Respiratory Isolation of US TB Suspects Anne Luetkemeyer 1 ; Cynthia Firnhaber 7 ; Michelle Kendall 2 ; XingyeWu 2 ; Debra Benator 3 ; Gerald Mazurek 4 ; Diane Havlir 1 ; Beatriz Grinsztejn 5 ; David Alland 6 on behalf of the ACTG A5295/TBTC 34 StudyTeams 1 San Francisco General Hospital, University of California San Francisco, San Francisco, CA, US; 2 Harvard School of Public Health, Center for Biostatistics in AIDS Research, Boston, MA, US; 3 Washington DC Veterans Affairs Medical Center, Washington, DC, US; 4 US Centers for Disease Control and Prevention, Atlanta, GA, US; 5 Instituto de Pesquisa Clinica Evandro Chagas, Rio de Janiero, Brazil; 6 Rutgers New Jersey Medical School, Newark, NJ, US; 7 University of Witswatersrand, Johannesburg, South Africa; 8 ACTG A5295/TBTC 34 Study Teams, N/a, MA, US 825 Needle Autopsies Highlight Challenges in Defining HIV+ TB Deaths Using Verbal Autopsy Aaron Karat 1 ; MphoTlali 2 ; Salome Charalambous 2 ; Kerrigan McCarthy 2 ;Violet Chihota 2 ; Gavin Churchyard 2 ; Katherine Fielding 1 ; Kathleen Kahn 3 ;Tanvier Omar 4 ; Alison Grant 1 1 London School of Hygiene and Tropical Medicine, London, United Kingdom; 2 The Aurum Institute, Johannesburg, South Africa; 3 University of the Witwatersrand, Johannesburg, South Africa; 4 National Health Laboratory Service, Wits School of Public Health, Johannesburg, South Africa Nathan C. Bahr 1 ; Ryan Halupnick; Grace Linder; Reuben Kiggundu 2 ; HenryW. Nabeta 2 ; DarlishaWilliams 1 ; Srinand Srevatsan 3 ; Joshua Rhein 1 ; David B. Meya 2 ; David R. Boulware 1 1 University of Minnesota, Minneapolis, MN, US; 2 Makerere University College of Health Sciences, Kampala, Uganda; 3 University of Minnesota, Minneapolis, MN, US 827LB Adherence to Once-Weekly Self-Administered INH and Rifapentine for Latent TB: iAdhere Robert Belknap 1 ; Andrey Borisov 2 ; David Holland 3 ; Pei-Jean Feng 2 ; Joan-Pau Millet 4 ; Neil Martinson 5 ; AliciaWright 6 ; Michael Chen 2 ; Joan Cayla 4 ; Jose M. Mida 7 and theTuberculosisTrials Consortium (TBTC) 1 Denver Health and Hospital Authority, Denver, CO, US; 2 US Centers for Disease Control and Prevention, Altanta, GA, US; 3 Emory University, Atlanta, GA, US; 4 Tuberculosis Investigation Unit of Barcelona, Barcelona, Spain; 5 University of Witwatersrand, Johannesburg, South Africa; 6 Vanderbilt University, Nashville, TN, US; 7 Hospital Clinic–IDIBAPS, University of Barcelona, Barcelona, Spain 828LB Wirelessly Observed Therapy (WOT): A New Paradigm in TB Therapy Monitoring Sara Browne 1 ; Richard Haubrich 1 ; Kathleen S. Moser 2 ; Lorenzo DiCarlo 3 ; Charles A. Peloquin 4 ; Constance A. Benson 1 1 University of California San Diego, San Diego, CA, US; 2 San Diego County Health and Human Services Agency, San Diego, CA, US; 3 Proteus Digital Health Inc, Redwood City, CA, US; 4 University of Florida College of Pharmacy, Gainesville, FL, US 826 Delta-Like 1 Protein, Vitamin D Binding Protein, and Fetuin Measurement in Cerebrospinal Fluid for Detection of Mycobacterium tuberculosis Meningitis

2:30 pm– 4:00 pm TB Adverse Events, Recurrence, and Mortality 829 Severe Adverse Events in Outpatient Drug-Resistant TB Treatment in South Africa Rebecca H. Berhanu 1 ; Kathryn Schnippel 2 ; Andrew Black 3 ; Erika Mohr 4 ; Busi Mncube 1 ; Ian Sanne 1 1 Health Economics and Epidemiology Research Organisation, Johannesburg, South Africa; 2 Right to Care, Johannesburg, South Africa; 3 Reproductive Health Institute, University of Witswatersrand, Johannesburg, South Africa; 4 Médecins Sans Frontières, Cape Town, South Africa 830 Decreased TB Recurrence After Introduction of ART in Durban, South Africa Yuri F. van der Heijden 1 ; Farina Karim 2 ; Gary Parker 2 ;Tilagavathy Chinappa 3 ; Grace Mufamadi 3 ; Linda Zako 3 ; Bryan E. Shepherd 1 ;Timothy Sterling 1 ; Alexander Pym 2 1 Vanderbilt University, Nashville, TN, US; 2 KwaZulu Natal Research Institute for TB and HIV (K-RITH), Durban, South Africa; 3 Ethekwini Municipality, Durban, South Africa 831 Incidence of Active Tuberculosis in HIV-Infected Adults and Mortality in Thailand 1 Institut de Recherche Pour le Développement UMI 174-PHPT, Chiang Mai, Thailand; 2 Mahasarakham Hospital, Mahasarakham, Thailand; 3 Hat Yai Hospital, Hat Yai, Thailand; 4 Phaholpolpayuhasaena Hospital, Kanchanaburi, Thailand; 5 Kalasin Hospital, Kalasin, Thailand 832 Antiretroviral Scale-up and Tuberculosis Mortality in High-Burden Countries Eline Korenromp 2 ; Eran Bendavid 1 ; IsabelYan 1 1 Stanford University, Stanford, CA, US; 2 Futures Institute, Glastonbury, CT, US 833 Culture-Negative TB Is AssociatedWith Increased Mortality in HIV- Infected Persons Timothy Sterling 1 ; Cathy Jenkins 1 ; Karu Jayathilake 1 ; Eduardo Gotuzzo 2 ;ValdileaVeloso 3 ; Claudia P. Cortes 4 ; Denis Padgett 5 ; Brenda Crabtree-Ramirez 6 ; Bryan E. Shepherd 1 ; Catherine Nicolas Salvadori 1 ; Suwalai Chalermpantmetagul 1 ; Julie Figoni 1 ; SuchartThongpaen 2 ; Ampaipith Nilmanat 3 ; Patinun Chirawatthanaphan 4 ; PramualThaingamsilp 5 ;Tim R. Cressey 1 ; Nicole Ngo-Giang-Huong 1 ; Gonzague Jourdain 1

Poster Listings

McGowan 1 CCASAnet

1 Vanderbilt University, Nashville, TN, US; 2 Universidad Peruana Cayetano Heredia, Lima, Peru; 3 Instituto Pequisa Evandro Chagas, Rio de Janeiro, Brazil; 4 University of Chile, Santiago, Chile; 5 Instituto Hondureno de Seguruidad Social, Tegucigalpa, Honduras; 6 Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico

THURSDAY, FEBRUARY 26, 2015 Session P-R5 Poster Session

Poster Hall

2:30 pm– 4:00 pm Cryptococcal Meningitis: Host Response, Treatment, and Outcomes 834 Local and Systemic Humoral Responses to Cryptococcal Meningitis in Patients With AIDS Erin E. Finn 1 ; Jordan Janoff 1 ; Jeremy Rahkola 1 ; David B. Meya 2 ; Samuel Okurut 2 ; Andrew D. Kambugu 2 ; Paul Bohjanen 3 ; Kirsten Nielsen 3 ; David R. Boulware 3 ; Edward N. Janoff 1 1 Mucosal and Vaccine Research Colorado, Aurora, CO, US; 2 Makerere University College of Health Sciences, Kampala, Uganda; 3 University of Minnesota, Minneapolis, MN, US 835 Antiretroviral Therapy Alters the CSF Immune Response in Cryptococcal Meningitis James E. Scriven 1 ; Britta Urban 1 ; Lisa Graham 2 ; Charlotte Schutz 2 ; Robert J.Wilkinson 3 ; David R. Boulware 4 ; David Lalloo 1 ; Graeme Meintjes 2 1 Liverpool School of Tropical Medicine, Liverpool, United Kingdom; 2 University of Cape Town, Cape Town, South Africa; 3 Imperial College London, London, United Kingdom; 4 University of Minnesota, Minneapolis, MN, US

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CROI 2015