CROI 2015 Program and Abstracts

Poster Listings

WEDNESDAY, FEBRUARY 25, 2015 Session P-P2 Poster Session

725 High Cancer Risk Among the HIV-Infected Elderly in the United States Elizabeth L. Yanik ; Hormuzd A. Katki; Eric A. Engels National Cancer Institute (NCI), Rockville, MD, US 726 Smoking Outweighs HIV-Related Risk Factors for Non–AIDS-Defining Cancers Keri N. Althoff 1 ; Stephen J. Gange 1 ; Chad Achenbach 2 ; Lisa P. Jacobson 1 ; Angel M. Mayor 3 ; Michael J. Silverberg 4 ; Amy Justice 5 ; Richard Moore 6 ;Yuezhou Jing 1 ; Kelly Gebo 6 On behalf of the North American AIDS Cohort Collaboration on Research and Design 1 Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, US; 2 Northwestern University, Feinberg School of Medicine, Chicago, IL, US; 3 Universidad Central del Caribe, Bayamon, US; 4 Kaiser Permanente Northern California, Oakland, CA, US; 5 Veterans Affairs Connecticut Healthcare System and Yale Schools of Medicine and Public Health, New Haven, CT, US; 6 Johns Hopkins University School of Medicine, Baltimore, MD, US 727 High Frequency of Early Lung Cancer Diagnosis With Chest CT in HIV- Infected Smokers Alain Makinson 1 ; Sabrina Eymard-Duvernay 2 ; François Raffi 3 ; Fabrice Bonnet 4 ; Laurence Thirard 5 ; PierreTattevin 6 ; Sophie Abgrall 7 ; Jacques Reynes 1 ;Vincent Le Moing 1 on behalf of the ANRS EP48 HIV CHEST StudyTeam 1 University Hospital Montpellier, UMI233, Montpellier, France; 2 UMI 233, IRD, University Montpellier 1, Montpellier, France; 3 Nantes University Hospital, Nantes, France; 4 University Hospital Bordeaux, Inserm U897, Bordeaux, France; 5 Tourcoing University Hospital, Tourcoing, France; 6 Pontchaillou University Hospital, Rennes, France; 7 University Hospital Avicennes, Bobigny, France; 8 ANRS, Paris, France 728 CD4 Measures as Predictors of Lung Cancer Risk and Prognosis in HIV Infection Keith Sigel 1 ; Kristina Crothers 2 ; Kirsha Gordon 3 ; Sheldon Brown 4 ; David Rimland 5 ; Maria Rodriguez-Barradas 6 ; Cynthia Gibert 7 ; Matthew B. Goetz 8 ; Roger Bedimo 9 ; Robert Dubrow 10 1 Icahn School of Medicine at Mount Sinai, New York, NY, US; 2 University of Washington School of Medicine, Seattle, WA, US; 3 VA Connecticut Healthcare System and Yale University Schools of Medicine and Public Health, New Haven, CT, US; 4 James J. Peters VA Medical Center, Bronx, NY, US; 5 Atlanta VA Medical Center, Atlanta, GA, US; 6 Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, US; 7 Washington DC Veterans Affairs Medical Center, Washington, DC, US; 8 Los Angeles VA Medical Center, Los Angeles, CA, US; 9 Veterans Affairs North Texas Health Care System, Dallas, TX, US; 10 Yale University School of Public Health, New Haven, CT, US 2:30 pm– 4:00 pm Cardiovascular Disease Outcomes 729 Cardiovascular Disease Mortality Among HIV-Infected Persons, New York City, 2001–2012 David B. Hanna 1 ; Chitra Ramaswamy 2 ; Robert C. Kaplan 1 ; Regina Zimmerman 2 ; Sarah L. Braunstein 2 1 Albert Einstein College of Medicine, Bronx, NY, US; 2 New York City Department of Health and Mental Hygiene, Long Island City, NY, US 730 Angiographic Restenosis After PTCA in HIV-Infected Patients: Incidence and Predictors Dominik Promny 3 ; Christoph D. Spinner 1 ; Salvatore Cassese 2 ; Isabell Bernlochner 3 ; Christian Bradaric 3 ; Karl-Ludwig Laugwitz 3 ; Adnan Kastrati 2 ; Simon Schneider 3 1 University Hospital Klinikum Rechts der Isar, Munich, Germany; 2 Deutsches Herzzentrum Muenchen, Munich, Germany; 3 University Hospital Klinikum Rechts der Isar, Munich, Germany TUESDAY, FEBRUARY 24, 2015 Session P-P1 Poster Session Poster Hall

Poster Hall

2:30 pm– 4:00 pm Dyslipidemia: Mediators and Treatment 731 PCSK9 Is Elevated in HIV+ Patients and May Mediate HIV-Associated Dyslipidemia Payal Kohli 1 ; Peter Ganz 1 ;Yifei Ma 1 ; Rebecca Scherzer 1 ; Kristinalisa Maka 1 ; Scott Wasserman 2 ; Rob Scott 2 ; Priscilla Hsue 1 1 University of California San Francisco, San Francisco, CA, US; 2 Amgen, Thousand Oaks, CA, US 732 Enhanced, Not Inhibited Monocyte Cholesterol Efflux Characterises Untreated HIV Jane A. O’Halloran 2 ;Therese Herlihy 2 ; Alan Macken 2 ; Louise Rainford 2 ; John S. Lambert 2 ; Gerard J. Sheehan 2 ; Niall G. Mahon 2 ; Leo P. Lawler 2 ; PatrickW. Mallon 2 1 University College Dublin, Dublin, Ireland; 2 University College Dublin, Dublin, Ireland; 3 University College Dublin, Dublin, Ireland; 4 University College Dublin, Dublin, Ireland; 5 University College Dublin, Dublin, Ireland 733 Rosuvastatin vs Protease Inhibitor Switch for Hypercholesterolemia: Randomised Trial Frederick J. Lee 7 ; Polyana Monteiro 3 ; David Baker 1 ; Mark Bloch 2 ; Robert Finlayson 8 ; Richard Moore 5 ; Norman Roth 6 ; Jennifer F. Hoy 4 ; Esteban Martinez 3 ; Andrew Carr 7 1 East Sydney Doctors, Sydney, Australia; 2 Holdsworth House Medical Practice, Sydney, Australia; 3 Hospital Clinic, University of Barcelona, Barcelona, Spain; 4 Monash University/Alfred Hospital, Melbourne, Australia; 5 Northside Clinic, Melbourne, Australia; 6 Prahran Market Clinic, Melbourne, Australia; 7 St. Vincent’s Hospital, Sydney, Australia; 8 Taylor Square Private Clinic, Sydney, Australia 734 Application of New ACC/AHA Cholesterol Guidelines to an HIV Clinical Care Cohort Mosepele Mosepele 4 ; Susan Regan 1 ; James B. Meigs 1 ; Steven Grinspoon 1 ;Virginia A.Triant 1 1 Massachusetts General Hospital, Harvard Medical School, Boston, MA, US; 2 Massachusetts General Hospital, Harvard Medical School, Boston, MA, US; 3 Massachusetts General Hospital, Harvard Medical School, Boston, MA, US; 4 Harvard School of Public Health, Boston, MA, US 2:30 pm– 4:00 pm ART: Cardiovascular Risk and Hypertension 735 ICAM-1 Overexpression Induced by Abacavir is Mediated by P2X 7 Receptors Carmen de Pablo;Victor Collado-Diaz; Samuel Orden; Cesar Rios-Navarro; Juan Esplugues; Angeles Alvarez University of Valencia, Valencia, Spain 736 Changes in Platelet Function Following Abacavir Administration: A Pilot Study Janine M. Trevillyan 2 ; Elizabeth E. Gardiner 2 ; Jane F. Arthur 2 ; Jing Jing 2 ; Robert K. Andrews 2 ; Jennifer F. Hoy 2 1 Monash University, Melbourne, Australia; 2 Monash University, Melbourne, Australia 737 An RCT of Rilpivirine vs Efavirenz on Cardiovascular Risk in Healthy Volunteers Samir K. Gupta 1 ; James E. Slaven 1 ; Ziyue Liu 1 1 Indiana University School of Medicine, Indianapolis, IN, US; 2 Indiana University, School of Medicine, Indianapolis, IN, US 738 Elvitegravir Reduces Monocyte Activation and Vascular Inflammation More Than Efavirenz Corrilynn O. Hileman 1 ; Bruce Kinley 1 ;Valeska Scharen-Guivel 2 ; Kathy Melbourne 2 ; Javier Szwarcberg 2 ; Janet Robinson 1 ; Michael M Lederman 1 ; Grace A. McComsey 1 1 Case Western Reserve University, Cleveland, OH, US; 2 Gilead Sciences, Inc., Foster City, CA, US Session P-P3 Poster Session Poster Hall

Poster Listings

57

CROI 2015